추천 제품
분석
~98% (TLC)
Quality Level
양식
powder
solubility
chloroform: 20 mg/mL, clear, colorless
저장 온도
−20°C
SMILES string
O=C(CCCCCCC/C=C\CCCCCCCC)NCCO
InChI
1S/C20H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)21-18-19-22/h9-10,22H,2-8,11-19H2,1H3,(H,21,23)/b10-9-
InChI key
BOWVQLFMWHZBEF-KTKRTIGZSA-N
유전자 정보
human ... CNR1(1268) , CNR2(1269) , PPARA(5465) , TRPV1(7442)
mouse ... Cnr2(12802)
rat ... Cnr1(25248)
일반 설명
Oleoylethanolamide (OEA) is an endogenous fatty acid ethanolamine. Small intestine cells, adipose tissues, neurons and astrocytes produces OEA.
애플리케이션
N-Oleoylethanolamine has been used to study its effects on glucagon-like peptide (GLP)-1RA-mediated anorectic signaling and weight loss.
생화학적/생리학적 작용
Oleoylethanolamide (OEA) is a lipid mediator, which helps to control various biological functions, like food intake. It modulates the gene expression in the small intestine. OEA has the ability to initiate several receptors, such as cannabinoid receptor type 1 (CB1), peroxisome proliferator-activated receptors (PPARs) and G protein-coupled receptor 119 (GPR119).
Peroxisome proliferator-activator receptor α (PPARα) agonist
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
개인 보호 장비
dust mask type N95 (US), Eyeshields, Gloves
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시험 성적서(COA)
Lot/Batch Number
이미 열람한 고객
Byung-Koo Son et al.
Nanomaterials (Basel, Switzerland), 9(7) (2019-07-13)
A mixture of nanothin exfoliated (NTE) graphite and urea (CO(NH2)2) powder was treated with radio frequency (RF) thermal plasma to achieve in situ purification and nitrogen doping of NTE graphite using the high-temperature flame of the RF plasma. Reactive species
Oleoylethanolamide modulates glucagon-like peptide-1 receptor agonist signaling and enhances exendin-4-mediated weight loss in obese mice
Brown JD, et al.
American Journal of Physiology. Regulatory, Integrative and Comparative Physiology, 315(4), R595-R608 (2018)
The Gastrointestinal Tract and Control of Food Intake
Physiology of the Gastrointestinal Tract, 2, 1963-1978 (2012)
Xiaotong Diao et al.
Nature communications, 13(1), 2529-2529 (2022-05-10)
Hypoxia-inducible factors (HIFs) are α/β heterodimeric transcription factors modulating cellular responses to the low oxygen condition. Among three HIF-α isoforms, HIF-3α is the least studied to date. Here we show that oleoylethanolamide (OEA), a physiological lipid known to regulate food
Stefania Petrosino et al.
British journal of pharmacology, 173(7), 1154-1162 (2015-01-20)
Palmitoylethanolamide (PEA) is an endogenous congener of anandamide and potentiates its actions at cannabinoid CB1 and CB2 receptors, and at transient receptor potential vanilloid type-1 (TRPV1) channels. The other endocannabinoid, 2-arachidonoylglycerol (2-AG), was recently suggested to act as a TRPV1
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