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애플리케이션
Poly(deoxyadenylic-thymidylic) (Poly(dA-dT) • Poly(dA-dT))acid is a double-stranded alternating copolymer DNA model for conformational studies of DNA structure dynamics and drug interaction.
기타 정보
Double-stranded alternating copolymer.
단위 정의
One unit will yield an A260 of 1.0 in 1.0 ml 20 mM sodium phosphate/100 mM NaCl, pH 7.0 (1cm light path).
수량
One mg is equivalent to ≥12 A260 units.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
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시험 성적서(COA)
Lot/Batch Number
Marta Airoldi et al.
Journal of biomolecular structure & dynamics, 25(1), 77-84 (2007-08-07)
The thermal denaturation of the synthetic high molecular weight double stranded polynucleotide poly(dA-dT) x poly(dA-dT) has been studied in aqueous buffered solution (Tris 1.0 mM; pH 7.8+/-0.2) in the presence of increasing concentrations of either Ni(2+) (borderline cation) or Cd(2+)
M Vorlícková et al.
Journal of biomolecular structure & dynamics, 3(1), 67-83 (1985-08-01)
The article reviews data indicating that poly(dA-dT).poly(dA-dT) is able of adopting three distinct double helical structures in solution, of which only the A form conforms to classical notions. The other two structures have dinucleotides as double helical repeats. At low
Marta Airoldi et al.
Chirality, 20(9), 951-960 (2008-02-05)
The thermal behavior of the synthetic, high molecular weight, double stranded polynucleotides poly(dA-dT).poly(dA-dT) [polyAT] and poly(dG-dC).poly(dG-dC) [polyGC] solubilized in the aqueous core of the quaternary water-in-oil cationic microemulsion CTAB|n-pentanol|n-hexane|water in the presence of increasing amounts of NiCl(2) at several constant
Natasha McStay et al.
Nucleic acids research, 45(2), 527-540 (2016-12-03)
Herein we report the synthesis of tripodal C
Creina Slator et al.
ACS chemical biology, 11(1), 159-171 (2015-10-22)
The in cellulo catalytic production of reactive oxygen species (ROS) by copper(II) and iron(II) complexes is now recognized as a major mechanistic model in the design of effective cytotoxins of human cancer. The developmental complex, [Cu(o-phthalate)(1,10-phenanthroline)] (Cu-Ph), was recently reported
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