PRS2501

Anti-CIKS antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• 동의어(들): Anti-TRAF3 Interacting protein 2
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 형태: buffered aqueous solution
• 분자량: predicted mol wt 63 kDa
• 종 반응성: human
• 기술: immunofluorescence: suitable; immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• UniProt 수납 번호: O43734
• 배송 상태: dry ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... TRAF3IP2(10758)

설명

일반 설명

CIKS (connection to IKK (IκB kinase) and SAPK (stress-activated protein kinase) /JNK (jun kinase)) is a cytoplasmic protein, that exists in the nucleus. It is also termed as Act1(NF-κB activator 1) and TRAF3IP2 (TRAF3 interacting protein 2). It is located on chromosome 6q21.

면역원

a synthetic peptide corresponding to amino acids 2-15 of human CIKS.

생화학적/생리학적 작용

CIKS (connection to IKK (IκB kinase) and SAPK (stress-activated protein kinase) /JNK (jun kinase)) is susceptible to various diseases like psoriasis and psoriatic arthritis. It is responsible for the cardiomyocyte growth, fibroblast migration and proliferation, promoted by aldosterone. It participates in the signaling function of IL-17 (interleukin) cytokine family. It can act as a transcriptional enhancer due to its presence in the nuclear compartment of airway epithelial cells.

결합

The action of this antibody can be blocked using blocking peptide SBP2501.

물리적 형태

Solution in phosphate buffered saline containing 0.02% sodium azide

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable