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Merck
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Key Documents

RAB0278

Sigma-Aldrich

Rat IL-1 β ELISA Kit

for cell and tissue lysates

동의어(들):

Il-1 beta, Interleukin-1 beta

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About This Item

UNSPSC 코드:
41116158
NACRES:
NA.32

종 반응성

rat

포장

kit of 96 wells (12 strips x 8 wells)

기술

ELISA: suitable
capture ELISA: suitable

입력

sample type cell lysate
sample type tissue lysate

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 80 pg/mL
standard curve range: 68.59-50000 pg/mL

검출 방법

colorimetric

배송 상태

wet ice

저장 온도

−20°C

유전자 정보

rat ... Il1b(24494)

일반 설명

The Rat IL-1 β ELSA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Rat IL-1β cell lysate and tissue lysate.

면역원

Recombinant Rat IL-1 β

애플리케이션

For research use only. Not for use in diagnostic procedures

Rat IL-1 Β ELISA Kit has been used to measure IL-1 Β levels .
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

생화학적/생리학적 작용

Pro-inflammatory cytokine IL-1 Β (IL1B), which is highly expressed on Β-adrenoreceptor in obese adipose tissues, is implicated in induction of uncoupling protein 1 (UCP1) expression via extracellular signal-regulated kinase (ERK) activation in adipocytes. Macrophage autophagy inhibits the production of inflammasome-dependent IL-1Β and thereby it plays a vital role in reducing acute toxin-induced liver injury and death. In rats, IL-1Β enhanced neurogenesis and plasticity of carotid bodies (CB) by triggering ERK1/2 activation. IL-1Β plays a vital role in alteration of glomerular hemodynamics via stimulating the production of prostaglandin E2 (PGE2) in the mesangial cells.

기타 정보

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

키트 구성품 역시 별도로 이용 가능함

제품 번호
설명
SDS

  • RABDIL6ELISA 5X Sample Diluent Buffer (Item D2)SDS

  • RABELADEELISA 5X Assay/Sample Diluent Buffer E (Item E2)SDS

  • RABLYSIS12X Cell Lysis Buffer (Item J)SDS

  • RABSTOP3ELISA Stop Solution (Item I)SDS

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS

  • RABWASH420X Wash Buffer (Item B)SDS

픽토그램

Corrosion

신호어

Warning

유해 및 위험 성명서

예방조치 성명서

Hazard Classifications

Met. Corr. 1

Storage Class Code

8A - Combustible corrosive hazardous materials


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Diosmin Modulates the NF-kB Signal Transduction Pathways and Downregulation of Various Oxidative Stress Markers in Alloxan-Induced Diabetic Nephropathy.
Ahmed S
Inflammation null
Proinflammatory cytokine interleukin-1? suppresses cold-induced thermogenesis in adipocytes.
Goto T
Cytokine null
Macrophage autophagy limits acute toxic liver injury in mice through down regulation of interleukin-1?.
Ilyas G
Journal of Hepatology null
Interleukin-1? promotes the neurogenesis of carotid bodies by stimulating the activation of ERK1/2.
Xue F
Respiratory Physiology & Neurobiology null
Tormentic acid inhibits H2O2-induced oxidative stress and inflammation in rat vascular smooth muscle cells via inhibition of the NF-?B signaling pathway.
Wang YL
Molecular Medicine Reports null

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