추천 제품
종 반응성
mouse
포장
kit of 96 wells (12 strips x 8 wells)
기술
ELISA: suitable
입력
sample type cell culture supernatant(s)
sample type serum
sample type plasma
assay range
inter-assay cv: <10%
intra-assay cv: <12%
sensitivity: 0.1 ng/mL
검출 방법
colorimetric
배송 상태
wet ice
저장 온도
−20°C
유전자 정보
mouse ... Esm1(71690)
일반 설명
This ELISA antibody pair detects mouse Endothelial Cell-specific Molecule 1. Endothelial cell-specific molecule 1 (ESM1) is a secreted dermatan sulfate proteoglycan. This cysteine-rich protein is expressed in kidney glomeruli, specifically in renal epithelia and endothelial cells. Proangiogenic factors and cytokines modulate its activity.
애플리케이션
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
생화학적/생리학적 작용
Endothelial cell-specific molecule 1 (ESM1) may have a role in inflammation and angiogenesis. It has been linked to tumor growth. ESM1 stimulates vascular sprouting, growth, differentiation, migration and adhesion of cells.
기타 정보
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
신호어
Warning
유해 및 위험 성명서
예방조치 성명서
Hazard Classifications
Met. Corr. 1
Storage Class Code
8A - Combustible corrosive hazardous materials
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Murine glomerular transcriptome links endothelial cell-specific molecule-1 deficiency with susceptibility to diabetic nephropathy.
PLoS ONE (2017)
Hhex is a direct repressor of endothelial cell-specific molecule 1 (ESM-1).
Biochemical and Biophysical Research Communications (2006)
The non glycanated endocan polypeptide slows tumor growth by inducing stromal inflammatory reaction.
Oncotarget (2015)
ESM1 mediates NGFR-induced invasion and metastasis in murine oral squamous cell carcinoma.
Oncotarget (2016)
Esm1 modulates endothelial tip cell behavior and vascular permeability by enhancing VEGF bioavailability.
Circulation Research (2014)
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