추천 제품
종 반응성
human
포장
kit of 96 wells (12 strips x 8 wells)
기술
ELISA: suitable
입력
sample type cell culture supernatant(s)
sample type plasma
sample type serum
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 8 pg/mL
standard curve range: 8.19-2000 pg/mL
검출 방법
colorimetric
배송 상태
wet ice
저장 온도
−20°C
유전자 정보
human ... LDLR(3949)
일반 설명
The antibody pair provided in this kit recognizes human Low-density Lipoprotein Receptor.
LDLR (low density lipoprotein receptor) codes for a transmembrane receptor glycoprotein, containing 860 amino acids and is mapped to human chromosome 19p13.2.
LDLR (low density lipoprotein receptor) codes for a transmembrane receptor glycoprotein, containing 860 amino acids and is mapped to human chromosome 19p13.2.
애플리케이션
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
생화학적/생리학적 작용
LDLR′s (low density lipoprotein receptor) major function is to regulate the level of lipoprotein particles by mediating the clearance of LDL-cholesterol and triglyceride through receptor mediated endocytosis. LDLR is involved in proliferation by providing cholesterol for membrane synthesis. The LDLR gene is a target for treating cardiovascular diseases. Mutation in the gene causes familial hypercholesterolemia.
기타 정보
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
신호어
Warning
유해 및 위험 성명서
예방조치 성명서
Hazard Classifications
Met. Corr. 1
Storage Class Code
8A - Combustible corrosive hazardous materials
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
5-Azacytidine engages an IRE1?-EGFR-ERK1/2 signaling pathway that stabilizes the LDL receptor mRNA.
Mnasri N, et al.
Biochimica et Biophysica Acta - Gene Regulatory Mechanisms, 1861(1), 29-40 (2018)
Daniel S Hsia et al.
The British journal of nutrition, 124(6), 577-585 (2020-04-18)
Cranberries are high in polyphenols, and epidemiological studies have shown that a high-polyphenol diet may reduce risk factors for diabetes and CVD. The present study aimed to determine if short-term cranberry beverage consumption would improve insulin sensitivity and other cardiovascular
Mutational screening in the LDLR gene among patients presenting familial hypercholesterolemia in the Southeast of Brazil.
Molfetta G A, et al.
Genetics and molecular research : GMR, 16(3) (2017)
Functional analysis of the p.(Leu15Pro) and p.(Gly20Arg) sequence changes in the signal sequence of LDL receptor.
Pavlouskova J, et al.
Atherosclerosis, 250, 9-14 (2016)
E Soemirien Kasanmoentalib et al.
Journal of neuroinflammation, 16(1), 279-279 (2019-12-31)
The complement system is a vital component of the inflammatory response occurring during bacterial meningitis. Blocking the complement system was shown to improve the outcome of experimental pneumococcal meningitis. Complement factor H (FH) is a complement regulatory protein inhibiting alternative
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