추천 제품
생물학적 소스
rabbit
Quality Level
결합
unconjugated
항체 형태
Ig fraction of antiserum
항체 생산 유형
primary antibodies
클론
polyclonal
양식
buffered aqueous solution
종 반응성
human
기술
immunohistochemistry: 1:50-1:100
indirect ELISA: 1:1000
NCBI 수납 번호
UniProt 수납 번호
배송 상태
dry ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... SOST(50964)
일반 설명
Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of the sclerostin gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.
면역원
SOST (NP_079513, 139-173)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human SOST.
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human SOST.
물리적 형태
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Anke M de Leeuw et al.
Frontiers in bioengineering and biotechnology, 12, 1310289-1310289 (2024-02-29)
Human organotypic bone models are an emerging technology that replicate bone physiology and mechanobiology for comprehensive in vitro experimentation over prolonged periods of time. Recently, we introduced a mineralized bone model based on 3D bioprinted cell-laden alginate-gelatin-graphene oxide hydrogels cultured
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