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Merck
모든 사진(3)

Key Documents

SAB2500328

Sigma-Aldrich

Anti-DPP4/CD26 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

동의어(들):

Anti-ADABP, Anti-ADCP2, Anti-Adenosine deaminase complexing protein 2, Anti-CD26, Anti-Dipeptidyl-peptidase 4

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About This Item

MDL number:
UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

goat

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

형태

buffered aqueous solution

종 반응성

human, mouse, rat, canine

기술

flow cytometry: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

UniProt 수납 번호

배송 상태

dry ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... DPP4(1803)

일반 설명

Dipeptidyl peptidase 4 (DPP4), also known as cluster of differentiation 26 (CD26), is localized on T- cell surface and interacts with adenosine deaminase (ADA), collagen and CD459. The gene encoding this protein is localized on human chromosome 2q24.2.

면역원

Peptide with sequence C-PPHFDKSKKYP from the internal region of the protein sequence according to NP_001926.2.

생화학적/생리학적 작용

Dipeptidyl peptidase 4 (DPP4) or CD26 plays a vital role in T cell co-stimulation, cell-to-cell adhesion and in human immunodeficiency virus (HIV) infection. It functions as a serine protease enzyme that catalyzes the cleavage of dipeptides from peptides containing proline or alanine residues. This protein is a biomarker and therapeutic target for asthma. Deletion of the DPP4 gene affects carbohydrate metabolism which in turn leads to mental retardation and hypotonia. Abnormal expression of the protein is observed during liver regeneration, cirrhosis and liver tumorigenesis. Also, DPP4 level is reduced in serum of chronic obstructive pulmonary disease (COPD) patients.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Molecular analyses of human and rat dipeptidyl peptidase IV.
Abbott CA
Advances in Experimental Medicine and Biology (1997)
Natacha Bohin et al.
Stem cell reports, 15(1), 156-170 (2020-06-13)
Intestinal crypts have great capacity for repair and regeneration after intestinal stem cell (ISC) injury. Here, we define the cellular remodeling process resulting from ISC niche interruption by transient Notch pathway inhibition in adult mice. Although ISCs were retained, lineage
A novel deletion in 2q24.1q24.2 in a girl with mental retardation and generalized hypotonia: a case report.
Palumbo O
Molecular Cytogenetics (2012)
Unravelling the immunological roles of dipeptidyl peptidase 4 (DPP4) activity and/or structure homologue (DASH) proteins
Wagner L
Clinical and Experimental Immunology (2016)
Expression and Clinical Significance of Serum Dipeptidyl Peptidase IV Chronic Obstructive Pulmonary Disease.
Chang XY
The American Journal of the Medical Sciences (2016)

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