추천 제품
생물학적 소스
goat
Quality Level
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
양식
buffered aqueous solution
종 반응성
human
기술
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
UniProt 수납 번호
배송 상태
dry ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... IGF1(3479)
일반 설명
Insulin-like growth factor 1 (IGF1) is a single polypeptide chain protein with three disulfide bridges. It is mainly produced by the liver and a wide range of extra-hepatic tissues. IGF1 is seen in normal and neoplastic breasts. The IGF1 gene is 84779 bp long and is made of 6 different exons. IGF-1 gene is located on human chromosome 12q23.2.
면역원
Peptide with sequence RSVRAQRHTD, from the internal region of the protein sequence according to NP_001104753.1; NP_001104754.1; NP_001104755.1; NP_000609.1
애플리케이션
Anti-IGF1 antibody produced in goat has been used in western blotting.
생화학적/생리학적 작용
Insulin-like growth factor 1 (IGF1) protein is essential for the development of children and adults. It plays a crucial role in general anabolic processes. IGF1 participates in differentiation and cell proliferation. It plays a key role in osteogenesis, muscle repair, and hypertrophy after trauma. IGF1 is also involved in the generation of axons in nerves and regeneration of a nerve after ischemic insult. It is known to participate in the clinical sequelae of Laron′s dwarfism. IGF1 is required for normal breast development.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
The pharmacogenomics journal, 16(1), 102-106 (2015-04-15)
Short children using growth hormone (GH) to accelerate their growth respond to this treatment with a variable efficacy. The causes of this individual variability are multifactorial and could involve epigenetics. Quantifying the impact of epigenetic variation on response to treatments
IGF1 (Insulin-Like Growth Factor 1 (Somatomedin C))
Atlas of Genetics and Cytogenetics in Oncology and Haematology (2013)
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