추천 제품
생물학적 소스
mouse
Quality Level
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
GT1315, monoclonal
형태
buffered aqueous solution
분자량
189kDa
종 반응성
human
농도
1mg/mL
기술
western blot: 1:500-1:3000
동형
IgG1
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... CEP152(22995)
일반 설명
CEP152 (centrosomal protein 152), a mammalian ortholog of Drosphila asterless is a component of mammalian centrosomes. It is located on human chromosome 15.
면역원
Recombinant protein encompassing a sequence within the N-terminus region of human CEP152.
애플리케이션
Suggested starting dilutions are as follows: WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
생화학적/생리학적 작용
This gene encodes a protein that is thought to be involved with centrosome function. Mutations in this gene have been associated with primary microcephaly (MCPH4). Alternative splicing results in multiple transcript variants. [provided by RefSeq]
CEP152 (centrosomal protein 152) plays an important role in cell division and development. It is highly essential for the recruitment of centriole of Plk4 (polo-like kinase 4) and centriole duplication at the time of cell cycle.
CEP152 (centrosomal protein 152) plays an important role in cell division and development. It is highly essential for the recruitment of centriole of Plk4 (polo-like kinase 4) and centriole duplication at the time of cell cycle.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
기타 정보
Purification: Affinity purified by Protein G
물리적 형태
Phosphate-buffered saline, no preservative added.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Primary autosomal recessive microcephaly: homozygosity mapping of MCPH4 to chromosome 15.
American Journal of Human Genetics, 65(5), 1465?1469-1465?1469 (1999)
Mutations in centrosomal protein CEP152 in primary microcephaly families linked to MCPH4.
American Journal of Human Genetics, 87(1), 40-51 (2010)
Human Cep192 and Cep152 cooperate in Plk4 recruitment and centriole duplication.
Journal of Cell Science, 126(14), 3223-3233 (2013)
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