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Merck
모든 사진(3)

주요 문서

SAB3500204

Sigma-Aldrich

Anti-CX3CR1 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

동의어(들):

Anti-V28

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About This Item

MDL number:
UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

양식

buffered aqueous solution

분자량

predicted mol wt 50 kDa

종 반응성

mouse, human, rat

기술

flow cytometry: suitable
immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

NCBI 수납 번호

UniProt 수납 번호

배송 상태

dry ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... CX3CR1(1524)

일반 설명

C-X3-C motif chemokine receptor 1(CX3CR1) is a seven transmembrane domain G‐protein‐coupled receptor. The gene is located on human chromosome 3p22.2. CX3CR1 is expressed in different types of inflammatory cells.

면역원

CX3CR1 antibody was raised against a peptide corresponding to amino acids 2 to 21 of human CX3CR1. The sequence differs from those of mouse and rat CX3CR1 by four amino acids (3,4).

애플리케이션

Anti-CX3CR1 antibody produced in rabbit has been used in western blotting.

생화학적/생리학적 작용

C-X3-C motif chemokine receptor 1 (CX3CR1) functions as a receptor for fractalkine. It is implicated in the progression of inflammatory and vascular disorders.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

결합

The action of this antibody can be blocked using blocking peptide SBP3500204.

물리적 형태

Supplied in PBS with 0.02% sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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관련 제품

제품 번호
설명
가격

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Polymorphisms in the microglial marker molecule CX3CR1 affect the blood volume of the human brain
Sakai M, et al.
Psychiatry and Clinical Neurosciences, 72(6), 409-422 (2018)
Leucine-rich repeat kinase-2 (LRRK2) modulates paraquat-induced inflammatory sickness and stress phenotype
Rudyk C, et al.
Journal of Neuroinflammation, 16(1), 120-120 (2019)
Chris Rudyk et al.
Journal of neuroinflammation, 16(1), 120-120 (2019-06-09)
Leucine-rich repeat kinase 2 (LRRK2) is a common gene implicated in Parkinson's disease (PD) and is also thought to be fundamentally involved in numerous immune functions. Thus, we assessed the role of LRRK2 in the context of the effects of
Glabridin Therapy Reduces Chronic Allodynia, Spinal Microgliosis, and Dendritic Spine Generation by Inhibiting Fractalkine-CX3CR1 Signaling in a Mouse Model of Tibial Fractures.
Long, et al.
Brain sciences, 13 (2023)
Merlin G Butler et al.
International journal of molecular sciences, 16(3), 6464-6495 (2015-03-25)
Recently, autism-related research has focused on the identification of various genes and disturbed pathways causing the genetically heterogeneous group of autism spectrum disorders (ASD). The list of autism-related genes has significantly increased due to better awareness with advances in genetic

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