SAB3500929

Anti-RIFT VALLEY FEVER VIRUS antibody produced in rabbit

affinity isolated antibody

• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 양식: buffered aqueous solution
• 종 반응성: virus
• 농도: 1 mg/mL
• 기술: ELISA: suitable
• UniProt 수납 번호: P03518
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified

설명

일반 설명

Rift valley fever virus (RVFV) is an enveloped RNA virus belonging to the Phlebovirus genus of the family Bunyaviridae. RVFV possesses a single stranded segmented RNA genome composed of a large (L), a medium (M), and a small (S) segment. The L segment codes for the RNA-dependent RNA polymerase. The M segment codes for a polyprotein which is the precursor to the glycoproteins G1 and G2 and two non-structural proteins, 14K and 78K. The S segment codes for the nucleoprotein N and the non-structural protein NSs.

면역원

Antibody was raised against a 20 amino acid synthetic peptide near the center of the RVF virus.

생화학적/생리학적 작용

Rift valley fever virus (RVFV) causes rift valley fever (RVF), an arthropod-borne viral disease. The virus is transmitted either by an arthropod or direct transmission by contact or aerosol among the hosts. The non-structural phosphoprotein (NSs) is responsible for the virulence in the pathogenic RVFV and suppresses human interferon gene expression. The fever is mainly observed in sheep and cattle. In humans, RVF clinical symptoms includes benign fever to severe encephalitis, retinitis, and fatal hepatitis with haemorrhagic fever. RVFV may block α/β interferon (IFN-α/β) expression in host and may target transcription factor aswell TFIIH.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

결합

The action of this antibody can be blocked using blocking peptide SBP3500929.

물리적 형태

Supplied at 1 mg/mL in PBS with 0.02% sodim azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable