SAB4200682

Anti-Human IgG (Fc specific) antibody, Mouse monoclonal

clone GG-7, purified from hybridoma cell culture

• 동의어(들): Monoclonal Anti-Human IgG (Fc specific) antibody produced in mouse
• UNSPSC 코드: 12352203
• NACRES: NA.46

속성

• 생물학적 소스: mouse
• Quality Level: 300
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: GG-7, monoclonal
• 양식: buffered aqueous solution
• 종 반응성: human
• 농도: ~1 mg/mL
• 기술: ELISA: suitable; immunofluorescence: suitable; indirect ELISA: 0.25-0.5 μg/mL using 5μg/mL human IgG for coating.
• 동형: IgG1
• 배송 상태: dry ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified

설명

일반 설명

Monoclonal Anti-Human IgG (Fc specific) (mouse IgG1 isotype) is derived from the GG-7 hybridoma, produced by the fusion of mouse myeloma cells and splenocytes from mouse immunized with Purified human IgG myeloma proteins covalently coupled to polyaminostyrene (PAS) microbeads. IgGs are the most common Immunoglobulins isotype in blood, lymph fluid, cerebrospinal fluid, and peritoneal fluid. IgGs include four subclasses (IgG1, IgG2, IgG3, and IgG4), they consist of a variable Fab fragment (which includes the antibody recognition site), and a conserved Fc fragment.

면역원

Purified human IgG myeloma proteins covalently coupled to polyaminostyrene (PAS) microbeads

애플리케이션

Monoclonal Anti-Human IgG (Fc specific) antibody has been used in:

• ELISA
• Imprint Immunofixation (IIF)
• Immunofluorometric Assay (IFMA)
• Hemagglutination (HA)
• Hemagglutination Inhibition (HAI)
• Particle Counting Immunoassay (PACIA)
• detection of cytoplasmic IgG

생화학적/생리학적 작용

The crystallizable fragment (Fc) of IgG has various important functions such as complement fixation, site for rheumatoid factor (autoantibody directed to Fc) attachment, passage through the placental membrane and protein A binding. IgG deficiencies are often associated with various diseases.

물리적 형태

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable