SAB4200764

Anti-Dystrophin Antibody

mouse monoclonal, MANDYS8

• 동의어(들): Anti-DMD
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 제품명: Anti-Dystrophin antibody, Mouse monoclonal, clone MANDYS8, purified from hybridoma cell culture
• 생물학적 소스: mouse
• Quality Level: 200
• 항체 형태: purified from hybridoma cell culture
• 항체 생산 유형: primary antibodies
• 클론: MANDYS8, monoclonal
• 양식: buffered aqueous solution
• 분자량: ~427 kDa
• 종 반응성: porcine, rabbit, mouse, rat, human
• 향상된 검증: independent; Learn more about Antibody Enhanced Validation
• 농도: ~1.0 mg/mL
• 기술: immunoblotting: suitable; immunohistochemistry: 5-10 μg/mL using acetone fixed rat tongue frozen sections
• 동형: IgG2b
• UniProt 수납 번호: P11532
• 배송 상태: dry ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... DMD(1756)

설명

일반 설명

Anti-Dystrophin antibody, Mouse monoclonal (mouse IgG2b isotype) is derived from the MANDYS8 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from mouse immunized with fragment of recombinant human dystrophin. Dystrophin is a 427 kD protein which joins the actin cytoskeleton to laminin. It possesses multiple domains and is localized to the extracellular matrix. Dystrophin contains NH2-terminal domain for actin binding. The C-terminal domain interacts with dystrophin associated protein (DAP).

Dystrophin is a rod-shaped cytoskeletal protein located to the periphery (plasma membrane) of normal striated muscle fibers.

특이성

Anti-Dystrophin antibody, Mouse monoclonal specifically recognizes an epitope located on the rod domain of the human dystrophin molecule.

면역원

recombinant human dystrophin

애플리케이션

Anti-Dystrophin antibody, Mouse monoclonal has been used in immunoblotting and immunohistochemistry.

생화학적/생리학적 작용

Dystrophin is known to prevent muscle fibre injury due to contraction.

물리적 형태

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide as preservative.

기타 정보

This product is for R&D use only, not for drug, household, or other uses.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: nwg
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable