SAB4300094

Anti-phospho-FOXO1 (pSer²⁵⁶) antibody produced in rabbit

affinity isolated antibody

• 동의어(들): Anti-FKH1 antibody produced in rabbit, Anti-FKHR antibody produced in rabbit, Anti-FOXO1A antibody produced in rabbit, Anti-forkhead box O1 antibody produced in rabbit
• MDL number: MFCD03791549
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 형태: buffered aqueous solution
• 분자량: 78-82 kDa
• 종 반응성: rat, human, mouse
• 농도: 1 mg/mL
• 기술: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; indirect immunofluorescence: 1:100-1:200; western blot: 1:500-1:1000
• 동형: IgG
• 면역원 서열: (A-A-SP-M-D)
• NCBI 수납 번호: NP_002006.2
• UniProt 수납 번호: Q12778
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: phosphorylation (pSer256)
• 유전자 정보: human ... FOXO1(2308)

설명

일반 설명

FOXO1 (forkhead box O1) is encoded by the gene mapped to human chromosome 13q14. The encoded protein is a transcription factor and is a member of the Foxo subfamily.

면역원

Peptide sequence around phosphorylation site of serine 256 (A-A-S(p)-M-D), according to the protein FOXO1.

애플리케이션

Anti-phospho-FOXO1 (pSer256) antibody produced in rabbit has been used in western blotting.

생화학적/생리학적 작용

FOXO1 (forkhead box O1) blocks the differentiation of cell in fetal pancreatic progenitor cells. It controls the differentiation of adipocytes. FOXO1 is involved in the insulin regulation of glucose-6-phosphatase (G6p) expression. Additionally, this protein plays a vital role in tumor suppression by inducing growth arrest and apoptosis.

특징 및 장점

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표적 설명

Transcription factor.

물리적 형태

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable