SAB4500827

Anti-Factor VIII antibody produced in rabbit

affinity isolated antibody

• 동의어(들): AHF, F8B, F8C, antihemophilic factor, coagulation factor VIII
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 형태: buffered aqueous solution
• 분자량: antigen 267 kDa
• 종 반응성: mouse, human
• 농도: ~1 mg/mL
• 기술: ELISA: 1:10000; western blot: 1:500-1:1000
• NCBI 수납 번호: P00451
• UniProt 수납 번호: P00451
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... F8(2157)

설명

일반 설명

Anti-Factor VIII Antibody detects endogenous levels of total Factor VIII protein.

Blood clotting factor VIII (FVIII), a nonenzymatic cofactor of activated factor IX (FIXa) is of ~330 kDa. It has three homologous A-domains, a unique B-domain and two C-domains. It is located on chromosome Xq28.

면역원

The antiserum was produced against synthesized peptide derived from human Factor VIII.

Immunogen Range: 2161-2210

생화학적/생리학적 작용

Mutation in the factor VIII gene (F8) results in haemophilia A (HA). Higher levels of VIII:C (FVIII:C) leads to venous and arterial thromboembolism. The factor VIII serve as a procoagulant cofactor in the intrinsic blood coagulation pathway.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: nwg
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable