추천 제품
생물학적 소스
rabbit
Quality Level
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
형태
buffered aqueous solution
분자량
antigen 150 kDa
종 반응성
human, rat, mouse
농도
~1 mg/mL
기술
ELISA: 1:40000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
phosphorylation (pTyr1333)
유전자 정보
human ... FLT1(2321)
일반 설명
Vascular endothelial growth factor (VEGF) is also known as vascular permeability factor or vasculotropin. It is a 46kDa homodimeric peptide growth factor. This gene is located on human chromosome 13q12.
면역원
The antiserum was produced against synthesized peptide derived from human VEGFR1 around the phosphorylation site of Tyr1333.
Immunogen Range: 1289-1338
Immunogen Range: 1289-1338
애플리케이션
Anti-phospho-VEGFR1 (pTyr1333) antibody has been used in immunostaining.
생화학적/생리학적 작용
Vascular endothelial growth factor (VEGF) activates endothelial cell growth in vitro and angiogenesis in vivo by binding to endothelial cells. This protein participates in endothelial proliferation, regulation of vascular permeability and thrombogenicity.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Gestational diabetes mellitus is associated with increased pro-migratory activation of vascular endothelial growth factor receptor 2 and reduced expression of vascular endothelial growth factor receptor 1
Troncoso F, et al.
PLoS ONE (2017)
Maryam Farzaneh Behelgardi et al.
Scientific reports, 8(1), 17924-17924 (2018-12-19)
Interfering with interactions of vascular endothelial growth factors (VEGFs) with their receptors (VEGFRs) effectively inhibits angiogenesis and tumor growth. We designed an antagonist peptide of VEGF-A and VEGF-B reproducing two discontinuous receptor binding regions of VEGF-B (loop 1 and loop3)
VEGF165b Modulates Endothelial VEGFR1-STAT3 Signaling Pathway and Angiogenesis in Human and Experimental Peripheral Arterial Disease
Ganta VC, et al.
Circulation Research, 120(2), 282-295 (2017)
The genetic differences between gallbladder and bile duct cancer cell lines
Saito S, et al.
Oncology Reports, 16(5), 949-956 (2006)
Aya Yamamura et al.
Frontiers in pharmacology, 12, 667474-667474 (2021-05-08)
Vascular endothelial growth factor (VEGF) signaling plays a critical role in the carcinogenesis and tumor development of several cancer types. However, its pathological significance in prostate cancer, one of the most frequent and lethal malignancies in men, remains unclear. In
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