추천 제품
생물학적 소스
rabbit
Quality Level
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
형태
buffered aqueous solution
분자량
antigen 51 kDa
종 반응성
human, mouse, rat
농도
~1 mg/mL
기술
ELISA: 1:40000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
phosphorylation (pThr196/pThr200)
유전자 정보
human ... CAMK4(814)
일반 설명
Calcium/calmodulin-dependent protein kinase IV (CAMK4) is a multifunctional serine/threonine protein kinase. It is present in cells of the nervous and immune systems. This gene is located on human chromosome 5q22.
면역원
The antiserum was produced against synthesized peptide derived from human CaMK4 around the phosphorylation site of Thr196/200.
Immunogen Range: 166-215
Immunogen Range: 166-215
생화학적/생리학적 작용
Calcium/calmodulin-dependent kinase 4 (CAMK4) controls blood pressure.This protein plays a major role in the spermatogenesis by phosphorylating protamines.. It controls vascular tone. Absence of CaMK4 gene promotes hypertension.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
CaMK4 Gene Deletion Induces Hypertension
Santulli G
Journal of the American Heart Association (2012)
Calcium/calmodulin-dependent kinase IV in immune and inflammatory responses: novel routes for an ancient traveller
Racioppi L and Means AR
Trends in Immunology, 29(12), 600-607 (2008)
CAMK4 gene variation is associated with hypertension in a Uygur population
Chen SZ, et al.
Genetics and molecular research : GMR, 15(1) (2016)
Akanksha Roy et al.
International journal of molecular sciences, 25(6) (2024-03-28)
Inherited retinal degenerative diseases (IRDs) are a group of rare diseases that lead to a progressive loss of photoreceptor cells and, ultimately, blindness. The overactivation of cGMP-dependent protein kinase G (PKG), one of the key effectors of cGMP-signaling, was previously
Genetic risk factors for the development of allergic disease identified by genome-wide association
Portelli MA, et al.
Clinical and Experimental Allergy, 45(1), 21-31 (2015)
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