추천 제품
생물학적 소스
mouse
결합
unconjugated
항체 형태
purified immunoglobulin
항체 생산 유형
primary antibodies
클론
S89-34, monoclonal
형태
buffered aqueous glycerol solution
분자량
antigen predicted mol wt 105-125 kDa
종 반응성
human, mouse, rat
농도
1 mg/mL
기술
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
동형
IgG1
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
rat ... Kcnb1(25736)
일반 설명
Potassium voltage-gated channel subfamily B member 1 (KCNB1) is widely distributed in the central nervous system. The gene ID for the protein is 25736.
특이성
Detects ~105-125 kDa (varies with cell background due to phosphorylation). No crossreactivity to rat Kv2.2.
면역원
Synthetic peptide amino acids 837-853 (cytoplamsic Cterminus) of rat KV2.1(HMLPGGGAHGSTRDQSI),Accession Number NP_037318.
생화학적/생리학적 작용
Potassium voltage-gated channel subfamily B member 1 (KCNB1) forms microdomains to aid in protein trafficking and has a role in smooth muscle contraction. KCNB1 also takes part in membrane fusion activities. Studies on Chinese hamster ovary (CHO) cells have shown that this protein has a role in apoptosis.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
Solution in PBS, pH 7.4, 50% glycerol, and 0.09% sodium azide
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Anastasia Grizel et al.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 9(5), 727-739 (2014-09-27)
Voltage-gated potassium Kv2.1 channels are widely distributed in the central nervous system, specifically in neuroendocrine and endocrine cells. Their cytoplasmic C-termini are large and carry out many important functions. Here we provide the first direct structural evidence that each C-terminal
Kv2.1 cell surface clusters are insertion platforms for ion channel delivery to the plasma membrane.
Emily Deutsch et al.
Molecular biology of the cell, 23(15), 2917-2929 (2012-06-01)
Voltage-gated K(+) (Kv) channels regulate membrane potential in many cell types. Although the channel surface density and location must be well controlled, little is known about Kv channel delivery and retrieval on the cell surface. The Kv2.1 channel localizes to
Yasushi Hosoi et al.
Frontiers in molecular neuroscience, 15, 806798-806798 (2022-12-06)
Fetal and infant brains are rich in maternally derived taurine. We previously demonstrated that taurine action regulates the cation-chloride cotransporter activity and the differentiation and radial migration of pyramidal neuron progenitors in the developing neocortex of rodent fetuses. Here we
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