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Merck
모든 사진(3)

Key Documents

SAB5200888

Sigma-Aldrich

Monoclonal Anti-Glun2A/Nr2A antibody produced in mouse

clone S327-95, purified immunoglobulin

동의어(들):

Anti-GRIN2A, Anti-HNR2A, Anti-NMDA 2A

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

mouse

Quality Level

결합

unconjugated

항체 형태

purified immunoglobulin

항체 생산 유형

primary antibodies

클론

S327-95, monoclonal

형태

buffered aqueous solution

분자량

antigen predicted mol wt 170 kDa

종 반응성

mouse, human, rat

농도

1 mg/mL

기술

immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

동형

IgG2a

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

면역원

Fusion protein amino acids 75-325 (extracellular N-terminus) of rat GluN2A/NR2A

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

PBS pH7.4, 50% glycerol, 0.09% sodium azide

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Rebecca Krall et al.
Neuroscience letters, 790, 136896-136896 (2022-10-07)
Zinc, loaded into glutamate-containing presynaptic vesicles and released into the synapse in an activity-dependent manner, modulates neurotransmission through its actions on postsynaptic targets, prominently via high-affinity inhibition of GluN2A-containing NMDA receptors. Recently, we identified a postsynaptic transport mechanism that regulates
Annabel Romero-Hernandez et al.
Neuron, 92(6), 1324-1336 (2016-12-06)
Zinc is vastly present in the mammalian brain and controls functions of various cell surface receptors to regulate neurotransmission. A distinctive characteristic of N-methyl-D-aspartate (NMDA) receptors containing a GluN2A subunit is that their ion channel activity is allosterically inhibited by
Jeremiah D Paskus et al.
Cell reports, 29(10), 2944-2952 (2019-12-05)
The RhoGEFs Kalirin-7 and Trio are regulators of synaptic plasticity, and their dysregulation is associated with a range of neurodevelopmental and neurodegenerative disorders. Although studies have implicated both Kalirin and Trio in certain diseases, such as tauopathies, they remarkably differ

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