추천 제품
재조합
expressed in HEK 293 cells
Quality Level
항체 형태
purified immunoglobulin
항체 생산 유형
primary antibodies
클론
RM303, monoclonal
recombinant monoclonal
형태
buffered aqueous glycerol solution
종 반응성
human
기술
immunohistochemistry: 1:500-1:1000
western blot: 1:250-1:500
동형
IgG
NCBI 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... PDGFRB(5159)
일반 설명
The PDGFRB (platelet derived growth factor receptor β) gene is mapped to human chromosome 5q32. It encodes for a receptor tyrosine kinase.
특이성
This antibody reacts to human CD140b (PDGFR-beta) (Platelet-derived growth factor receptor beta).
면역원
A peptide corresponding to the C-terminus of human CD140b.
생화학적/생리학적 작용
PDGFRB (platelet derived growth factor receptor β) acts as a regulator of mesenchymal cells in tumour cells. Upregulation of the gene is observed in gastric cancer, breast and prostate cancers. Mutations in the gene is associated with infantile myofibromatosis.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
Solution in phosphate buffered saline containing 50% glycerol, 1% BSA and 0.09% sodium azide.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
PDGFRB gain-of-function mutations in sporadic infantile myofibromatosis.
Arts FA
Human Molecular Genetics, 26(10), 1801-1810 (2017)
A genome-wide map of aberrantly expressed chromosomal islands in colorectal cancer.
Staub E, et al.
Molecular Cancer, 5(1), 37-37 (2006)
Quantitative proteomic analysis of gastric cancer tissue reveals novel proteins in platelet-derived growth factor b signaling pathway.
Liu F
Oncotarget, 8(13), 22059-22075 (2017)
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