SAB5702163

Anti-STAT6 Antibody, clone 4G7J8, Rabbit Monoclonal

• 동의어(들): D12S1644,IL-4-STAT,STAT6B,STAT6C,STAT6
• UNSPSC 코드: 12352203
• NACRES: NA.46

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• material: colorless
• 클론: 4G7J8, monoclonal
• 양식: liquid
• 분자량: 100 kDa
• 종 반응성: mouse, mouse
• 농도: 0.8 mg/mL
• 기술: immunofluorescence: 1:50 - 1:200; immunoprecipitation (IP): 1:50 - 1:200; western blot: 1:500 - 1:2000
• 색상: colorless
• 동형: IgG
• UniProt 수납 번호: P42226
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... STAT6(6778)

설명

일반 설명

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]

면역원

A synthesized peptide derived from human STAT6

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

애플리케이션

WB, IF/ICC, IP

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1