추천 제품
분석
≥95% (HPLC)
양식
lyophilized
구성
Peptide Content, ≥75%
저장 조건
protect from light
저장 온도
−20°C
Amino Acid Sequence
Ac-Gln-Lys-Leu-Val-Phe-Phe-NH2
일반 설명
Amyloid plaques characteristic of the Alzheimer brain contain fibrils composed of amyloid β aggregates. Peptides, small organic molecules and nanoparticles can be used to bind or aggregate amyloid β (Aβ). They have been used as a strategy for the development of pharmaceutical approaches or agents to treat Alzheimer′s disease (AD). Short peptides containing the sequence KLVFF have been shown to bind specifically to the homologous region in Aβ and are used to prevent full length amyloid fibril formation.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Inhibition of amyloid-? aggregation in Alzheimer's disease.
Wang Q
Current Pharmaceutical Design (2014)
L O Tjernberg et al.
The Journal of biological chemistry, 272(19), 12601-12605 (1997-05-09)
We have previously shown that short peptides incorporating the sequence KLVFF can bind to the approximately 40amino acid residue Alzheimer amyloid beta-peptide (Abeta) and disrupt amyloid fibril formation (Tjernberg, L. O., Näslund, J., Lindqvist, F., Johansson, J., Karlström, A. R.
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