SML0283

Amorolfine hydrochloride

≥98% (HPLC)

• 동의어(들): (2R,6S)-rel-4-[3-[4-(1,1-Dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethyl-morpholine hydrochloride, Ro 14-4767/002
• 실험식(Hill 표기법): C₂₁H₃₅ON · HCl
• CAS Number: 78613-38-4
• Molecular Weight: 353.97
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329825291
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 형태: powder
• 저장 조건: desiccated
• 색상: white to beige
• solubility: DMSO: ≥5 mg/mL (warmed)
• 저장 온도: room temp
• SMILES string: Cl.CCC(C)(C)c1ccc(CC(C)CN2C[C@H](C)O[C@H](C)C2)cc1
• InChI: 1S/C21H35NO.ClH/c1-7-21(5,6)20-10-8-19(9-11-20)12-16(2)13-22-14-17(3)23-18(4)15-22;/h8-11,16-18H,7,12-15H2,1-6H3;1H/t16?,17-,18+;
• InChI key: XZKWIPVTHGWDCF-KUZYQSSXSA-N

설명

애플리케이션

Amorolfine hydrochloride has been used as an antifungal agent.

생화학적/생리학적 작용

Amorolfine blocks ergosterol biosynthesis by interfering with delta 14 reduction and the delta 7-8 isomerisation.

Amorolfine hydrochloride is a potential for treating onychomycosis infected nails by topical application. A 5% solution combination with fluconazole is effective on sensitive fungus in fingernail onychomycosis.

안전성 정보

• 픽토그램: GHS07,GHS09
• 신호어: Warning
• 유해 및 위험 성명서: H302,H315,H411
• 예방조치 성명서: P264 - P273 - P280 - P301 + P312 - P302 + P352 - P332 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 2 - Skin Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable