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Merck
모든 사진(1)

주요 문서

SML0476

Sigma-Aldrich

Rabeprazole sodium

≥98% (HPLC)

동의어(들):

2-([4-(3-Methoxypropoxy)-3-methylpyridin-2-yl]methylsulfinyl)-1H-benzo[d]imidazole, Pariprazole

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About This Item

실험식(Hill 표기법):
C18H20N3O3S · Na
CAS Number:
Molecular Weight:
381.42
UNSPSC 코드:
12352200
PubChem Substance ID:
NACRES:
NA.77

Quality Level

분석

≥98% (HPLC)

형태

powder

저장 조건

desiccated

색상

white to beige

solubility

H2O: 10 mg/mL (clear solution)

배송 상태

wet ice

저장 온도

−20°C

SMILES string

[Na+].COCCCOc1ccnc(CS(=O)c2nc3ccccc3[n-]2)c1C

InChI

1S/C18H20N3O3S.Na/c1-13-16(19-9-8-17(13)24-11-5-10-23-2)12-25(22)18-20-14-6-3-4-7-15(14)21-18;/h3-4,6-9H,5,10-12H2,1-2H3;/q-1;+1

InChI key

KRCQSTCYZUOBHN-UHFFFAOYSA-N

유전자 정보

유사한 제품을 찾으십니까? 방문 제품 비교 안내

애플리케이션

Rabeprazole sodium has been used as a proton pump inhibitor (PPI) to study its effects on spontaneous uterine contractile activity in pregnant women.

생화학적/생리학적 작용

Rabeprazole sodium is gastric proton pump inhibitor. It suppresses the production of acid in the stomach by inhibiting the gastric H+/K+ATPase (hydrogen-potassium adenosine triphosphatase) at the secretory surface of the gastric parietal cell. Rabeprazole sodium has been used clinically to treat acid-reflux disorders (GERD), peptic ulcer disease, H. pylori eradication, and prevent gastroinetestinal bleeds associated with NSAID use.

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 4

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

이미 열람한 고객

C Terranova et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 52, 125-131 (2013-11-13)
In this study we investigate in in vitro myometrial tissue samples of pregnant women: (a) the effects of proton pomp inhibitors (PPIs) (omeprazole, esomeprazole, pantoprazole, lansoprazole and rabeprazole) on spontaneous contractions; (b) the muscle-relaxant efficacy of the most active PPI
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Life sciences, 110(1), 35-43 (2014-07-06)
First; to develop rabeprazole (RP)-alginate core coated chitosan nanoparticles (NP) utilizing water in oil (W/O) nanoemulsion technique. Second; formulation of transdermal patches loaded RP-NP that avoid drug peroral acid sensitivity and first pass effect. The influence of six factors on

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