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Merck
모든 사진(1)

주요 문서

SML0512

Sigma-Aldrich

BLT-4

≥98% (HPLC)

동의어(들):

INF 271, MIT 9952-29, N-(2-Methoxyphenyl)-N′-2-naphthalenyl-urea

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About This Item

실험식(Hill 표기법):
C18H16N2O2
CAS Number:
Molecular Weight:
292.33
MDL number:
UNSPSC 코드:
51111800
PubChem Substance ID:
NACRES:
NA.77

Quality Level

분석

≥98% (HPLC)

양식

powder

색상

white to beige

solubility

DMSO: 15 mg/mL (clear solution)

저장 온도

room temp

SMILES string

COc1ccccc1NC(=O)Nc2ccc3ccccc3c2

InChI

1S/C18H16N2O2/c1-22-17-9-5-4-8-16(17)20-18(21)19-15-11-10-13-6-2-3-7-14(13)12-15/h2-12H,1H3,(H2,19,20,21)

InChI key

ISADADAHPHHLEM-UHFFFAOYSA-N

생화학적/생리학적 작용

BLT-4 is a blocker of lipid transport-4 (BLT-4). BLT-4 is a specific, reversible inhibitor of scavenger receptor, class B, type I (SR-BI) mediated lipid transfer. The molecule blocks the cellular uptake and transfer of cholesterol ester from HDL.

픽토그램

Environment

신호어

Warning

유해 및 위험 성명서

예방조치 성명서

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

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The common human pathogen Group A Streptococcus (GAS) causes superficial as well as invasive, life-threatening diseases. An increase in the occurrence of invasive GAS infection by strains of the M1 and M89 serotypes has been correlated with increased expression of
Thomas J F Nieland et al.
Journal of lipid research, 45(7), 1256-1265 (2004-04-23)
Scavenger receptor class B type I (SR-BI) and ABCA1 are structurally dissimilar cell surface proteins that play key roles in HDL metabolism. SR-BI is a receptor that binds HDL with high affinity and mediates both the selective lipid uptake of
Guillemette Maurin et al.
AIDS (London, England), 29(9), 1025-1033 (2015-07-01)
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