SML1169
Pitstop 2
≥98% (HPLC), powder, clathrin-mediated endocytosis inhibitor
동의어(들):
N-[5-[(4-Bromophenyl)methylene]-4,5-dihydro-4-oxo-2-thiazolyl]-1-naphthalenesulfonamide, Pitstop-2
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C20H13BrN2O3S2
CAS Number:
Molecular Weight:
473.36
UNSPSC 코드:
12352200
NACRES:
NA.77
추천 제품
제품명
Pitstop 2, ≥98% (HPLC)
Quality Level
분석
≥98% (HPLC)
양식
powder
색상
white to light brown
solubility
DMSO: 20 mg/mL, clear
저장 온도
−20°C
애플리케이션
Pitstop 2 has been used as an inhibitor of clathrin-mediated endocytosis.
생화학적/생리학적 작용
Pitstop 2 also has an ability to breakdown the nuclear pore complex (NPC) permeability barrier and decrease importin β binding along with alteration of the NPC ultrastructure. Pitstop 2 is also involved in the inhibition of platelet activation, platelet aggregation and secretion.
Pitstop 2 is a selective inhibitor of clathrin-mediated endocytosis that acts via blocking ligand access to the clathrin terminal domain. Pitstop 2 selectively inhibits clathrin-mediated HIV entry and stalls clathrin-coated pit (CCP) dynamics.
Pitstop 2 is a selective inhibitor of clathrin-mediated endocytosis.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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시험 성적서(COA)
Lot/Batch Number
이미 열람한 고객
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Clathrin inhibitor Pitstop-2 disrupts the nuclear pore complex permeability barrier
Liashkovich I, et al.
Scientific Reports, 5, 9994-9994 (2015)
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Gao W, et al.
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