SML1236

(−)-Nicotine hydrogen tartrate salt

≥98% (HPLC)

• 동의어(들): (−)-Nicotine ditartrate, (−)-1-Methyl-2-(3-pyridyl)pyrrolidine (+)-bitartrate salt
• 실험식(Hill 표기법): C₁₀H₁₄N₂ · 2C₄H₆O₆
• CAS Number: 65-31-6
• Molecular Weight: 462.41
• EC Number: 200-607-2
• UNSPSC 코드: 12352210
• PubChem Substance ID: 329825736
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 광학 활성: [α]/D +20 to +26°, c = 1.0 in water
• 저장 조건: desiccated
• 색상: white to beige
• solubility: H₂O: 20 mg/mL, clear
• 저장 온도: room temp
• SMILES string: CN1CCC[C@H]1C2=CC=CN=C2.C
• InChI: 1S/C10H14N2.CH4/c1-12-7-3-5-10(12)9-4-2-6-11-8-9;/h2,4,6,8,10H,3,5,7H2,1H3;1H4/t10-;/m0./s1
• InChI key: RYYKFQGHMYGLEL-PPHPATTJSA-N

설명

애플리케이션

(−)-Nicotine hydrogen tartrate salt has been used as an agonist for acetylcholine receptor (AChr).

(−)-Nicotine hydrogen tartrate salt has been used in intracellular calcium imaging.

생화학적/생리학적 작용

NHT is considered to be more stable than nicotine. Nicotine is highly addictive drug and is indirectly but strongly associated with tobacco related diseases. It helps to discontinue smoking. Nicotine might serve as a therapeutic agent in treating Alzheimer’s disease, Parkinson’s disease and ulcerative colitis.

Prototype nicotinic acetylcholine receptor agonist; naturally occurring isomer.

안전성 정보

• 픽토그램: GHS06,GHS08,GHS09
• 신호어: Danger
• 유해 및 위험 성명서: H301,H319,H330,H361d,H411
• 예방조치 성명서: P202 - P260 - P264 - P273 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Repr. 2
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 2
• Flash Point (°F): 289.8 °F
• Flash Point (°C): 143.2 °C