SML2248

SK-216

≥98% (HPLC)

• 동의어(들): 2-[5-[[6-[5-(1,1-Dimethylethyl)-2-benzoxazolyl]-2-naphthalenyl]oxy]pentyl]-propanedioic acid sodium salt, SK 216, [5-[[6-[5-(1,1-dimethylethyl)-2-benzoxazolyl]-2-naphthalenyl]oxy]pentyl]-propanedioic acid disodium salt
• 실험식(Hill 표기법): C₂₉H₂₉NNa₂O₆
• CAS Number: 654080-03-2
• Molecular Weight: 533.52
• UNSPSC 코드: 12352200

속성

• 분석: ≥98% (HPLC)
• 형태: powder
• 저장 조건: desiccated
• 색상: white to beige
• solubility: H₂O: 0.5 mg/mL, clear (warmed)
• 저장 온도: room temp
• SMILES string: CC(C)(C)C(C=C1)=CC2=C1OC(C3=CC=C4C(C=CC(OCCCCCC(C([O-])=O)C([O-])=O)=C4)=C3)=N2.[2Na+]
• InChI: 1S/C29H31NO6.2Na/c1-29(2,3)21-11-13-25-24(17-21)30-26(36-25)20-9-8-19-16-22(12-10-18(19)15-20)35-14-6-4-5-7-23(27(31)32)28(33)34;;/h8-13,15-17,23H,4-7,14H2,1-3H3,(H,31,32)(H,33,34);;/q;2*+1/p-2
• InChI key: YYTGMMYYLGKWIK-UHFFFAOYSA-L

설명

생화학적/생리학적 작용

SK-216 is an orally active potent and selective inhibitor of Plasminogen activator inhibitor-1 (PAI-1) that inhibits tumor progression and angiogenesis. SK-216 inhibits migration and tube formation of cultured human umbilical vein endothelial cells induced by various angiogenic factors. SK-116 prevents a formation of gastro-intestinal polyps in Min mice.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable