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Merck
모든 사진(2)

주요 문서

SML3709

Sigma-Aldrich

Tosufloxacin tosylate

≥98% (HPLC)

동의어(들):

7-(3-Amino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid 4-methylbenzenesulfonate, A 64730, A-61827, T 3262

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About This Item

실험식(Hill 표기법):
C19H15F3N4O3·C7H8O3S
CAS Number:
Molecular Weight:
576.54
MDL number:
UNSPSC 코드:
12352200
NACRES:
NA.21

Quality Level

분석

≥98% (HPLC)

형태

powder

저장 조건

desiccated

색상

white to beige

solubility

DMSO: 2 mg/mL, clear

저장 온도

-10 to -25°C

생화학적/생리학적 작용

Tosufloxacin tosylate is a synthetic fluoroquinolone broad spectrum antibiotic. Tosufloxacin potently inhibits bacterial DNA gyrase and topoisomerase IV. Tosufloxacin is indicated for the treatment of various infections such as skin, respiratory, urinary, gynecologic, ophthalmologic, otolaryngologic, dental infections.

주의사항

Hygroscopic

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

M A Cooper et al.
The Journal of antimicrobial chemotherapy, 29(6), 639-647 (1992-06-01)
The in-vitro activity of tosufloxacin (A-61827) was compared with that of temafloxacin, ciprofloxacin and selected members of other groups of antimicrobial agents, against 684 recent distinct clinical isolates and strains with known mechanisms of resistance. Against members of the Enterobacteriaceae
Masaru Usui et al.
Antimicrobial agents and chemotherapy, 63(6) (2019-04-03)
Formation of bacterial biofilms is a major health threat due to their high levels of tolerance to multiple antibiotics and the presence of persisters responsible for infection relapses. We previously showed that a combination of starvation and induction of SOS
Pengfei She et al.
Current microbiology, 79(1), 12-12 (2021-12-15)
Pseudomonas aeruginosa is a ubiquitous bacterium found in hospitals and the surrounding environment. The ability of P. aeruginosa to form biofilms confers high-level resistance to antibiotics, and the persister cells formed in the presence of high antibacterial drug concentrations make

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