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Merck
모든 사진(1)

주요 문서

U2875

Sigma-Aldrich

Uric acid sodium salt

동의어(들):

2,6,8-Trihydroxypurine, Sodium acid urate

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About This Item

Linear Formula:
C5H3N4O3Na
CAS Number:
Molecular Weight:
190.09
EC Number:
MDL number:
UNSPSC 코드:
41106305
PubChem Substance ID:
NACRES:
NA.51

생물학적 소스

microbial
synthetic

Quality Level

분석

11.0-13.0% anhydrous basis (Sodium, ICP)

양식

powder

solubility

1 M NaOH: 25 mg/mL, clear, colorless to faintly yellow

SMILES string

[Na].O=C1NC(=O)C2=C(N1)NC(=O)N2

InChI

1S/C5H4N4O3.Na.H/c10-3-1-2(7-4(11)6-1)8-5(12)9-3;;/h(H4,6,7,8,9,10,11,12);;

InChI key

IHMJZGFANDMEJM-UHFFFAOYSA-N

애플리케이션

Uric acid sodium salt has been used in isotonic solution of NaCl dose titration study. It has been used as a suspension in NaCl for intra-articular administration to experimental animals to induce synovitis.

생화학적/생리학적 작용

Sodium urate is the sodium salt of uric acid. In gout, it is observed in synovial fluid. Sodium urate has been shown to precipitate calcium oxalate from urine. It is also known to reverse the inhibitory effects of reactive oxygen and nitrogen metabolites on gelatinase A activity. Excess sodium urate in soft tissues results in a condition referred to as tophi.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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이미 열람한 고객

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1 of 2

Preferential accumulation of meloxicam in inflamed synovial joints of dogs
Johnston L and Narbe R
The Veterinary Record, vetrec-ve2011 (2012)
Jieru Han et al.
Journal of natural medicines, 75(1), 37-47 (2020-08-08)
Monosodium urate (MSU)-mediated inflammation is closely related to gouty arthritis (GA). Dioscin, an active ingredient, has been reported to possess anti-inflammatory property. Nevertheless, the role of dioscin in GA and the underlying mechanism have not been fully understood. In the
Linne & Ringsrud's Clinical Laboratory Science, 429-432 (2015)
Kim Gilbert et al.
The journal of trauma and acute care surgery, 86(3), 431-439 (2018-12-07)
Multiple organ failure can develop after hemorrhagic shock (HS). Uric acid (UA) is released from dying cells and can be proinflammatory. We hypothesized that UA could be an alternative mediator of organ apoptosis and inflammation after HS. Ventilated male Wistar
Dissolved urate salts out calcium oxalate in undiluted human urine in vitro: implications for calcium oxalate stone genesis
Grover PK, et al.
Chemistry & Biology, 10(3), 271-278 (2003)

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