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Merck
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주요 문서

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1445470

USP

Mometasone furoate

United States Pharmacopeia (USP) Reference Standard

동의어(들):

(11β,16α)-9,21-Dichloro-17-[(2-furanylcarbonyl)oxy]-11-hydroxy-16-methylpregna-1,4-diene-3,20-dione

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모든 사진(1)

About This Item

실험식(Hill 표기법):
C27H30Cl2O6
CAS Number:
83919-23-7
Molecular Weight:
521.43
MDL number:
MFCD00866003
UNSPSC 코드:
41116107
PubChem Substance ID:
329750487
NACRES:
NA.24

Grade

pharmaceutical primary standard

API family

mometasone

제조업체/상표

USP

응용 분야

pharmaceutical (small molecule)

형식

neat

SMILES string

C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@@]1(OC(=O)c5ccco5)C(=O)CCl

InChI

1S/C27H30Cl2O6/c1-15-11-19-18-7-6-16-12-17(30)8-9-24(16,2)26(18,29)21(31)13-25(19,3)27(15,22(32)14-28)35-23(33)20-5-4-10-34-20/h4-5,8-10,12,15,18-19,21,31H,6-7,11,13-14H2,1-3H3/t15-,18+,19+,21+,24+,25+,26+,27+/m1/s1

InChI key

WOFMFGQZHJDGCX-ZULDAHANSA-N

유전자 정보

human ... NR3C1(2908)

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일반 설명

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

애플리케이션

Mometasone furoate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

생화학적/생리학적 작용

Mometasone furoate is an anti-inflammatory glucocorticoid.

분석 메모

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

기타 정보

Sales restrictions may apply.

픽토그램

Health hazard
GHS08

신호어

Danger

유해 및 위험 성명서

H360D

Hazard Classifications

Repr. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Myron Zitt et al.
Drug safety, 30(4), 317-326 (2007-04-06)
The development of corticosteroids that are delivered directly to the nasal mucosa has alleviated much of the concern about the systemic adverse effects associated with oral corticosteroid therapy. However, given the high potency of these drugs and their widespread use
Anthony D'Urzo
Expert opinion on pharmacotherapy, 8(16), 2871-2884 (2007-10-25)
Mometasone furoate dry-powder inhaler (MF-DPI) is an inhaled corticosteroid (ICS) used for the treatment of persistent asthma in patients aged >or= 12 years. MF-DPI has low systemic bioavailability and high glucocorticoid receptor affinity compared with most other ICSs and modifies
Claudine M Baldwin et al.
Drugs, 68(12), 1723-1739 (2008-08-07)
Mometasone furoate (Nasonex) is a high-potency intranasal corticosteroid available for the treatment and/or prophylaxis of the nasal symptoms of seasonal allergic rhinitis (SAR) and perennial allergic rhinitis (PAR). In the EU, it is approved for use in patients aged >
Sherief R Janmohamed et al.
Journal of the American Academy of Dermatology, 70(6), 1076-1082 (2014-04-05)
Wet-wrap treatment (WWT) has been advocated as a relatively effective treatment in children with severe atopic dermatitis (AD). WWT often serves as crisis intervention for AD. We sought to evaluate the use of WWT with diluted corticosteroids in comparison with
Christian Grabow Westergaard et al.
Expert opinion on pharmacotherapy, 14(3), 339-346 (2013-02-01)
Asthma is a common chronic respiratory disease affecting the airways causing inflammation, airway hyperreactivity (AHR), and respiratory symptoms. Frequently, asthma can be effectively treated with inhaled corticosteroids (ICS) but in more severe cases additional drugs are required, such as long-acting
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