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Merck
  • Evaluation of the suppressive effect on bitter taste of gluconate.

Evaluation of the suppressive effect on bitter taste of gluconate.

Bioscience, biotechnology, and biochemistry (2012-12-12)
Masataka Narukawa, Tomoko Tsujitani, Yusuke Ueno, Kaori Nakano-Ooka, Nari Miyamoto-Kokubo, Shoko Sawano, Yukako Hayashi
초록

Gluconate is used as an additive in a wide range of processed foods. In this study, we investigated its utility as a taste-improving substance. To determine whether it has a suppressive effect on bitter taste, sensory evaluations were performed by human subjects. When gluconate was added to a quinine-HCl (QHCl) solution, the taste intensity decreased, but this effect was not observed when it was added to caffeine and to naringin solutions. Then we investigated the mechanism of suppression by performing behavioral and electrophysiological assays on mice. In mice, the addition of gluconate improved the taste preference for and reduced the gustatory nerve response to QHCl. In sum, gluconate had a suppressive effect on the bitter taste of QHCl, which might have been caused by depression of gustatory nerve activity.

MATERIALS
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제품 설명

Supelco
D-Gluconic acid sodium salt, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
Sigma-Aldrich
Sodium gluconate, meets USP testing specifications
Sigma-Aldrich
D-Gluconic acid solution, 49-53 wt. % in H2O
Sigma-Aldrich
D-Gluconic acid sodium salt, ≥99% (HPLC)
Supelco
Quinine, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
Supelco
Potassium gluconate, Pharmaceutical Secondary Standard; Certified Reference Material
Sigma-Aldrich
Quinine, suitable for fluorescence, anhydrous, ≥98.0% (dried material, NT)
Sigma-Aldrich
Quinine, 90%
Sigma-Aldrich
Iron(II) D-gluconate dihydrate, 98%
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Magnesium D-gluconate hydrate, ≥98% (HPLC)
Sigma-Aldrich
Potassium gluconate, 97.0-103.0% dry basis, meets USP testing specifications
Sigma-Aldrich
Magnesium D-gluconate hydrate, 98.0-102% anhydrous basis, meets USP testing specifications
Sigma-Aldrich
Potassium D-gluconate, ≥99% (HPLC)