145904

Quinine

90%

• 동의어(들): 6′-Methoxycinchonidine
• 실험식(Hill 표기법): C₂₀H₂₄N₂O₂
• CAS Number: 130-95-0
• Molecular Weight: 324.42
• Beilstein: 91867
• EC Number: 205-003-2
• MDL number: MFCD00198096
• UNSPSC 코드: 12352104
• PubChem Substance ID: 24848751
• NACRES: NA.22

속성

• Quality Level: 200
• 분석: 90%
• 광학 활성: [α]25/D −165°, c = 2 in ethanol
• mp: 173-175 °C (lit.)
• 작용기: hydroxyl
• SMILES string: COc1ccc2nccc([C@@H](O)[C@@H]3C[C@@H]4CCN3C[C@@H]4C=C)c2c1
• InChI: 1S/C20H24N2O2/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3/t13-,14-,19-,20+/m0/s1
• InChI key: LOUPRKONTZGTKE-WZBLMQSHSA-N
• 유전자 정보: human ... ABCB1(5243) , CYP2C9(1559) , CYP2D6(1565) ; rat ... Cyp2d1(266684) , Cyp2d2(25053) , Cyp2d3(24303) , Cyp2d4v1(171522)

설명

일반 설명

Quinine, a cinchona alkaloid found in the bark of the cinchona tree, is known for its anti-malarial property.

애플리케이션

Quinine has been used as a standard during the chemical evaluation of alkaloids in the hydroethanolic extracts of endophytic fungi obtained from the leaves of Costus spiralis by TLC.

Resolving agent for carboxylic acids. Catalyzes the kinetic resolution of furanones.

생화학적/생리학적 작용

Potassium channel blocker

기타 정보

remainder hydroquinine

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302,H317
• 예방조치 성명서: P261 - P264 - P272 - P280 - P301 + P312 - P302 + P352
• Hazard Classifications: Acute Tox. 4 Oral - Skin Sens. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Faceshields, Gloves