Q1250

Quinine hemisulfate salt monohydrate

synthetic, ≥90% (HPLC)

• 동의어(들): Quinine sulfate (2:1) (salt) dihydrate
• 실험식(Hill 표기법): C₂₀H₂₄N₂O₂ · 0.5H₂O₄S · H₂O
• CAS Number: 207671-44-1
• Molecular Weight: 391.47
• Beilstein: 6113937
• MDL number: MFCD00150790
• UNSPSC 코드: 12352210
• PubChem Substance ID: 57654578
• NACRES: NA.77

속성

• 생물학적 소스: synthetic
• Quality Level: 200
• 분석: ≥90% (HPLC)
• mp: ~225 °C (dec.) (lit.)
• solubility: H₂O: slightly soluble 1.2 mg/mL; ethanol: 8 mg/mL
• 항생제 활성 스펙트럼: parasites
• 동작 모드: enzyme | inhibits
• 주관자: Bayer
• SMILES string: O.O.OS(O)(=O)=O.COc1ccc2nccc([C@@H](O)C3CC4CCN3C[C@@H]4C=C)c2c1.COc5ccc6nccc([C@@H](O)C7CC8CCN7C[C@@H]8C=C)c6c5
• InChI: 1S/2C20H24N2O2.H2O4S.2H2O/c2*1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;1-5(2,3)4;;/h2*3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;(H2,1,2,3,4);2*1H2/t2*13-,14-,19-,20+;;;/m00.../s1
• InChI key: ZHNFLHYOFXQIOW-LPYZJUEESA-N

설명

애플리케이션

Quinine hemisulfate salt monohydrate has been used as a stimuli to evaluate its influence on sensory and cognitive factors.

생화학적/생리학적 작용

Potassium channel blocker. Antimalarial, anticholinergic, antihypertensive, and hypoglycemic agent; alkaloid originally isolated from the Cinchona family of South American trees. Inhibits mitochondrial ATP-regulated potassium channel. Used to study the metabolism of biocrystalized heme, hemozoin, in malarial parasites and to study the toxicity of heme (FP)-complexes.

Quinine has analgesic property.

특징 및 장점

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This compound was developed by Bayer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319,H335
• 예방조치 성명서: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves