MilliporeSigma

IL5

interleukin 5 (colony-stimulating factor, eosinophil)

Synonyms:
EDF, IL-5, TRF
Species:
UniProtKB ID:
Gene ID:
  • Human(3567) Summary: This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. [provided by RefSeq, Jul 2013]
  • Mouse(16191) interleukin 5
  • Rat(24497) interleukin 5
  • chicken(474360) interleukin 5 (colony-stimulating factor, eosinophil)
  • dog(403790) interleukin 5 (colony-stimulating factor, eosinophil)
  • domestic cat(493803) interleukin 5 (colony-stimulating factor, eosinophil)
  • Horse(100034199) interleukin 5 (colony-stimulating factor, eosinophil)
  • cow(280825) interleukin 5 (colony-stimulating factor, eosinophil)
  • sheep(443350) interleukin 5 (colony-stimulating factor, eosinophil)
  • domestic guinea pig(100135558) interleukin 5
  • naked mole-rat(101719528) interleukin 5 (colony-stimulating factor, eosinophil)

Custom & Knockdown Gene Products

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ELISA

Product Number
Description
Species
Feline IL5 / Interleukin-5 ELISA Kit, ,
Species
domestic cat
Human IL-5 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human
Mouse IL-5 ELISA Kit, for serum, plasma and cell culture supernatant,
Species
mouse
Rhesus Macaque IL5 / Interleukin-5 ELISA Kit, ,
Species

Small Molecule - Antagonist

Product Number
Description
Species
Budesonide, ≥99%,
Species
human, rat
Terfenadine, ,
Species
mouse, rat, human
Betamethasone, ≥98%,
Species
mouse, rat, human
Dexamethasone, powder, γ-irradiated, BioXtra, suitable for cell culture, ≥80% (HPLC),
Species
mouse, rat, human
Dexamethasone, powder, BioReagent, suitable for cell culture, ≥97%,
Species
mouse, rat, human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-IL5 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Anti-IL-5 Antibody, clone 4A1.6.15, ,
Species Reactivity
human
Application
immunohistochemistry
western blot

Proteins

Product Number
Description
Species
IL-5 from mouse, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
mouse
Interleukin-5 human, recombinant, expressed in baculovirus infected Sf21 cells, ≥97% (SDS-PAGE), lyophilized powder, suitable for cell culture,
Species
human
Interleukin-5 from mouse, ≥97% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture,
Species
mouse
IL-5 human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Il5,
Species
mouse