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B7777

Sigma-Aldrich

Budesonide

≥99%

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Synonym(s):
16,17-Butylidenebis(oxy)-11,21-dihydroxypregna-1,4-diene-3,20-dione
Empirical Formula (Hill Notation):
C25H34O6
CAS Number:
Molecular Weight:
430.53
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.77

Quality Level

assay

≥99%

form

powder

originator

AstraZeneca

SMILES string

[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@H]5OC(CCC)O[C@@]45C(=O)CO

InChI

1S/C25H34O6/c1-4-5-21-30-20-11-17-16-7-6-14-10-15(27)8-9-23(14,2)22(16)18(28)12-24(17,3)25(20,31-21)19(29)13-26/h8-10,16-18,20-22,26,28H,4-7,11-13H2,1-3H3/t16-,17-,18-,20+,21?,22+,23-,24-,25+/m0/s1

InChI key

VOVIALXJUBGFJZ-KWVAZRHASA-N

Gene Information

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This Item
F5021PHR1822PHR1178
Budesonide ≥99%

B7777

Budesonide

Flunisolide ≥97%

F5021

Flunisolide

Supelco

PHR1822

Budesonide Related Compound G

Budesonide Pharmaceutical Secondary Standard; Certified Reference Material

PHR1178

Budesonide

assay

≥99%

assay

≥97%

assay

-

assay

-

originator

AstraZeneca

originator

Roche

originator

-

originator

-

Gene Information

human ... IFNG(3458), IL5(3567), NR3C1(2908)
rat ... Nr3c1(24413)

Gene Information

-

Gene Information

-

Gene Information

human ... NR3C1(2908)

Biochem/physiol Actions

Budesonide is a second generation glucocorticoid with low systemic absorption. It is used as an anti-inflammatory agent in the treatment of asthma, rhinitis, and inflammatory bowel disease. It inhibits the expression of chemokine mRNA and production of eotaxin and RANTES protein in primary human bronchial epithelial cells. Budesonide is currently in clinical trials for the prevention of lung cancer. It shows inhibitory effects on benzo[a]pyrene-induced carcinogenesis of the lung in mice.

Features and Benefits

This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

pictograms

Health hazard

signalword

Warning

hcodes

Hazard Classifications

Repr. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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