MilliporeSigma

ATF4

activating transcription factor 4

Synonyms:
CREB-2, CREB2, TAXREB67, TXREB
Species:
UniProtKB ID:
Gene ID:
  • Human(468) Summary: This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication. [provided by RefSeq, Sep 2011]
  • Mouse(11911) activating transcription factor 4
  • Rat(79255) activating transcription factor 4
  • naked mole-rat(101724287) activating transcription factor 4
  • domestic cat(101084297) activating transcription factor 4 (tax-responsive enhancer element B67)
  • sheep(100216465) activating transcription factor 4 (tax-responsive enhancer element B67)
  • domestic guinea pig(100732296) activating transcription factor 4
  • cow(509107) activating transcription factor 4 (tax-responsive enhancer element B67)
  • dog(474503) activating transcription factor 4 (tax-responsive enhancer element B67)
  • chicken(395693) activating transcription factor 4 (tax-responsive enhancer element B67)

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ATF4 (AB2) antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
dog, human
Application
western blot
Monoclonal Anti-Atf4 - Atto 390 antibody produced in mouse, clone S360A-24, purified immunoglobulin,
Species Reactivity
human, rat
Application
immunocytochemistry
immunohistochemistry

western blot
Monoclonal Anti-Atf4 - Rpe antibody produced in mouse, clone S360A-24, purified immunoglobulin,
Species Reactivity
human, rat
Application
immunocytochemistry
immunohistochemistry

western blot
Monoclonal Anti-Atf4 - Atto 488 antibody produced in mouse, clone S360A-24, purified immunoglobulin,
Species Reactivity
human, rat
Application
immunocytochemistry
immunohistochemistry

western blot
Monoclonal Anti-Atf4 - Fitc antibody produced in mouse, clone S360A-24, purified immunoglobulin,
Species Reactivity
human, rat
Application
immunocytochemistry
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Atf4,
Species
mouse
MISSION® esiRNA, targeting human ATF4,
Species
human