MilliporeSigma

CBX1

chromobox homolog 1

Synonyms:
CBX, HP1-BETA, HP1Hs-beta, HP1Hsbeta, M31, MOD1, p25beta
Species:
UniProtKB ID:
Gene ID:
  • Human(10951) Summary: This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(12412) chromobox 1
  • Rat(360609) chromobox homolog 1
  • domestic cat(101084070) chromobox homolog 1
  • cow(616506) chromobox homolog 1
  • chicken(374237) chromobox homolog 1
  • naked mole-rat(101706928) chromobox homolog 1
  • dog(491051) chromobox homolog 1
  • domestic guinea pig(100716439) chromobox homolog 1
  • sheep(101116158) chromobox homolog 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CBX1/HP1-β antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
canine, human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Monoclonal Anti-CBX1 antibody produced in mouse, clone 4E12, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot
Anti-CBX1 Antibody, clone 1D7 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
bovine, canine, feline, human, monkey, mouse, porcine, rat
Application
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-Heterochromatin Protein-1 β Antibody, clone 1MOD-1A9, ascites fluid, clone 1MOD-1A9, Chemicon®,
Species Reactivity
human, mouse
Application
ELISA
immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-CBX1 (HP1 beta) Antibody, clone 5E9.1, clone 5E9.1, from mouse,
Species Reactivity
human
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CBX1,
Species
human