MilliporeSigma

CYP19A1

cytochrome P450, family 19, subfamily A, polypeptide 1

Synonyms:
ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM
Species:
UniProtKB ID:
Gene ID:
  • Human(1588) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants. [provided by RefSeq, Jul 2008]
  • Mouse(13075) cytochrome P450, family 19, subfamily a, polypeptide 1
  • Rat(25147) cytochrome P450, family 19, subfamily a, polypeptide 1
  • Goat(100861413) cytochrome P450, family 19, subfamily A, polypeptide 1
  • Horse(100009712) cytochrome P450, family 19, subfamily A, polypeptide 1
  • dog(494003) cytochrome P450, family 17, subfamily A, polypeptide 1
  • chicken(414854) cytochrome P450, family 19, subfamily A, polypeptide 1
  • Domestic Rabbit(100328545) cytochrome P450, family 19, subfamily A, polypeptide 1
  • cow(281740) cytochrome P450, family 19, subfamily A, polypeptide 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Cytochrome P450 19A1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-Aromatase Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
bovine, canine, chimpanzee, human, pig, porcine, rhesus macaque
Application
western blot
Anti-Aromatase (CYP19A1) Antibody, clone 5C5N7, Rabbit Monoclonal, ,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-CYP19A1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Anti-CYP19A1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot

Cell Lines

Product Number
Description
Species
CypExpress Aromatase, ,
Species
human

Small Molecule - Inhibitor

Product Number
Description
Species
Letrozole, European Pharmacopoeia (EP) Reference Standard,
Species
human
Letrozole, United States Pharmacopeia (USP) Reference Standard,
Species
human
Exemestane for peak identification, CRS, European Pharmacopoeia (EP) Reference Standard,
Species
human
Letrozole, ≥98% (HPLC),
Species
human
Letrozole, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human

Small Molecule - Ligand

Product Number
Description
Species
DL-Aminoglutethimide, ,
Species
human, rat

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Cyp19a1,
Species
mouse
MISSION® esiRNA, targeting human CYP19A1,
Species
human