CYP2E1
cytochrome P450, family 2, subfamily E, polypeptide 1
Synonyms:
CPE1, CYP2E, P450-J, P450C2E
Species:
Human CYP2E1 (1571), Mouse Cyp2e1 (13106), Rat Cyp2e1 (25086), sheep CYP2E1 (100568285), domestic cat CYP2E1 (554344), dog CYP2E1 (415128), cow CYP2E1 (282213), Horse CYP2E1 (100066422)
UniProtKB ID:
Gene ID:
- Human(1571) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer. [provided by RefSeq, Jul 2008]
- Mouse(13106) cytochrome P450, family 2, subfamily e, polypeptide 1
- Rat(25086) cytochrome P450, family 2, subfamily e, polypeptide 1
- sheep(100568285) cytochrome P450, family 2, subfamily E, polypeptide 1
- domestic cat(554344) cytochrome P450 2E1
- dog(415128) cytochrome P450, family 2, subfamily E, polypeptide 1
- cow(282213) cytochrome P450, family 2, subfamily E, polypeptide 1
- Horse(100066422) cytochrome P450, family 2, subfamily E, polypeptide 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CYP2E1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-CYP2E1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-Cytochrome P450 Enzyme CYP2E1 Antibody, serum, Chemicon®,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Cell Lines
Product Number
Description
Species
Proteins
Product Number
Description
Species
Cytochrome P450 human, 2E1 isozyme microsomes, with P450 Reductase and cytochrome b5, recombinant, expressed in baculovirus infected insect cells (BTI-TN-5B1-4),
Species
human
esiRNA
Product Number
Description
Species