MilliporeSigma

FGFR2

fibroblast growth factor receptor 2

Synonyms:
BBDS, BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25
Species:
UniProtKB ID:
Gene ID:
  • Human(2263) Summary: The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009]
  • Mouse(14183) fibroblast growth factor receptor 2
  • Rat(25022) fibroblast growth factor receptor 2
  • dog(415125) fibroblast growth factor receptor 2
  • domestic cat(101095198) fibroblast growth factor receptor 2
  • chicken(396259) fibroblast growth factor receptor 2
  • Zebrafish(352940) fibroblast growth factor receptor 2
  • naked mole-rat(101709077) fibroblast growth factor receptor 2
  • Domestic Rabbit(100009417) fibroblast growth factor receptor 2
  • Horse(100033956) fibroblast growth factor receptor 2
  • cow(404193) fibroblast growth factor receptor 2
  • domestic guinea pig(100379152) fibroblast growth factor receptor 2
  • sheep(443548) fibroblast growth factor receptor 2

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ELISA

Product Number
Description
Species
Phosphotyrosine FGFR2 / Fibroblast Growth Factor Receptor 2 ELISA Kit, ,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Fibroblast Growth Factor Receptor-2, Cytoplasmic antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-FGFR2 Mouse mAb (1G3), liquid, clone 1G3, Calbiochem®,
Species Reactivity
human
Application
Monoclonal Anti-FGFR2 antibody produced in mouse, clone 1G3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry

western blot
Anti-FGFR2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
immunohistochemistry

western blot
Anti-FGFR2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

Proteins

Product Number
Description
Species
FGFR2 (285-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥80% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
FGFR2 Protein, active, 10 µg, Active, N-terminal, His6-tagged, recombinant, human FGFR2, amino acids 456-770, for use in Kinase Assays.,
Species
human
FGFR2 (N549H) Protein, active, 10 µg, Active, N-terminal, 6His-tagged, recombinant, human FGFR2 (N549H), amino acids 456-770. For use in Kinase Assays.,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human FGFR2,
Species
human