MilliporeSigma

GRIN2A

glutamate receptor, ionotropic, N-methyl D-aspartate 2A

Synonyms:
EPND, GluN2A, NMDAR2A, NR2A
Species:
UniProtKB ID:
Gene ID:
  • Human(2903) Summary: N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
  • Mouse(14811) glutamate receptor, ionotropic, NMDA2A (epsilon 1)
  • Rat(24409) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • sheep(101106989) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • domestic guinea pig(100727265) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • dog(490012) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • chicken(427678) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • domestic cat(101086110) glutamate receptor, ionotropic, N-methyl D-aspartate 2A

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Agonist

Product Number
Description
Species
1,4-Bis(3-aminopropyl)piperazine, ≥99%,
Species
rat
Dextromethorphan hydrobromide, meets USP testing specifications,
Species
human
Dextromethorphan HBr, certified reference material, pharmaceutical secondary standard,
Species
human
Dextromethorphan solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Dextromethorphan hydrobromide, United States Pharmacopeia (USP) Reference Standard,
Species
human

Small Molecule - Allosteric Modulator

Product Number
Description
Species
4-Aminopiperidine, ,
Species
rat
S-(+)-Ketamine hydrochloride, ,
Species
human
(±)-Ketamine hydrochloride, solid,
Species
human
Ketamine hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Kainic acid monohydrate, ≥99% (TLC),
Species
human, mouse, rat

Small Molecule - Antagonist

Product Number
Description
Species
1-Adamantanemethylamine, 98%,
Species
human
1-Adamantylamine, 97%,
Species
human
Glycine, ACS reagent, ≥98.5%,
Species
rat
Glycine, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, ≥98.5%,
Species
rat
Glycine, BioXtra, ≥99% (titration),
Species
rat

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-Glun2A/Nr2A antibody produced in mouse, clone S327A-38, purified immunoglobulin,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Monoclonal Anti-Glun2A/Nr2A - Apc antibody produced in mouse, clone S327A-38, purified immunoglobulin,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Monoclonal Anti-Glun2A/Nr2A - Atto 488 antibody produced in mouse, clone S327A-38, purified immunoglobulin,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-GRIN2A antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-phospho NMDAR2A (Ser1459), ,
Species Reactivity
human
Application
immunocytochemistry
western blot

Small Molecule - Blocker

Product Number
Description
Species
N-(3,3-Diphenylpropyl)glycinamide, >98% (HPLC), solid,
Species
human
Agmatine sulfate salt, ≥97%, powder,
Species
human
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Species
human
Orphenadrine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Species
human
Orphenadrine hydrochloride, ≥98.0% (AT),
Species
human

Small Molecule - Inhibitor

Product Number
Description
Species
Indole-2-carboxylic acid, 98%,
Species
rat, human
1,3-Diphenylguanidine, 97%,
Species
rat, mouse, human
Quisqualic acid, powder,
Species
rat
Nω-Nitro-L-arginine, ≥98% (TLC),
Species
rat, mouse, human
Pentamidine isethionate salt, powder,
Species
human

Small Molecule - Mixed Agonist/Antagonist

Product Number
Description
Species
1,3-Diamino-2-propanol, 95%,
Species
rat
4-Amino-1-benzylpiperidine, 98%,
Species
rat
N,N′-Dimethyl-1,3-propanediamine, 97%,
Species
rat
N-Methyl-1,3-diaminopropane, 98%,
Species
rat
4-Amino-2,2,6,6-tetramethylpiperidine, 98%,
Species
rat

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Grin2a,
Species
mouse
MISSION® esiRNA, targeting human GRIN2A,
Species
human