IGF1R
insulin-like growth factor 1 receptor
CD221, IGFIR, IGFR, JTK13
Human IGF1R (3480), Mouse Igf1r (16001), Rat Igf1r (25718), domestic guinea pig Igf1r (100734840), chicken IGF1R (395889), naked mole-rat Igf1r (101710224), Horse IGF1R (100055698), domestic cat IGF1R (100500937), cow IGF1R (281848), dog IGF1R (442951)
- Human(3480) Summary: This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [provided by RefSeq, Jul 2008]
- Mouse(16001) insulin-like growth factor I receptor
- Rat(25718) insulin-like growth factor 1 receptor
- domestic guinea pig(100734840) insulin-like growth factor 1 receptor
- chicken(395889) insulin-like growth factor 1 receptor
- naked mole-rat(101710224) insulin-like growth factor 1 receptor
- Horse(100055698) insulin-like growth factor 1 receptor
- domestic cat(100500937) insulin-like growth factor 1 receptor
- cow(281848) insulin-like growth factor 1 receptor
- dog(442951) insulin-like growth factor 1 receptor
- sheep(443002) insulin-like growth factor 1 receptor
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Antibodies
Anti-IGF-1R β Antibody, clone 1D18 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
human, mouse, rat
affinity binding assay
flow cytometry
immunohistochemistry
western blot
flow cytometry
immunohistochemistry
western blot
Anti-IGF1R (Ab-1161) antibody produced in rabbit, affinity isolated antibody,
human, mouse, rat
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-phospho-IGF1R (pTyr1165/pTyr1166) antibody produced in rabbit, affinity isolated antibody,
human, mouse, rat
immunofluorescence
western blot
western blot
Anti-IGF-IRα subunit Antibody, from chicken, purified by affinity chromatography,
human, rhesus macaque
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-IGF-IR Antibody, clone JBW902, clone JBW902, Upstate®, from mouse,
human, mouse
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Small Molecule - Inhibitor
Proteins
IGF1R (960-end), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
human
IGF-IR (δ1-958) Protein, active, 20 µg, Active, N-terminal His6-tagged, recombinant human IGF-IR residues 959-end, for use in Kinase Assays.,
human
Insulin-like Growth Factor-I Receptor human, ≥95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
human