MilliporeSigma

NPPB

natriuretic peptide B

Synonyms:
BNP
Species:
UniProtKB ID:
Gene ID:
  • Human(4879) Summary: This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq, Jul 2008]
  • Mouse(18158) natriuretic peptide type B
  • Rat(25105) natriuretic peptide B
  • domestic cat(493764) natriuretic peptide B
  • dog(487441) natriuretic peptide B
  • chicken(395765) natriuretic peptide B
  • naked mole-rat(101718083) natriuretic peptide B
  • sheep(100294642) natriuretic peptide B
  • cow(508734) natriuretic peptide B

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ELISA

Product Number
Description
Species
Human NPPB / Natriuretic Peptides B ELISA Kit, for serum, plasma, cell culture supernatants and urine,
Species
human
Brain Natriuretic Peptide EIA Kit, for serum, plasma, culture supernatant and cell lysates,
Species
human
Human proNPPB / Natriuretic Peptides B ELISA Kit, for serum, plasma, cell culture supernatants and urine,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-human brain natriuretic peptide, clone 24, clone 24, from mouse,
Species Reactivity
human
Application
ELISA
western blot
Anti-Nppb Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
Anti-NPPB antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-hu N-term proBNP (NT-proBNP) clone 154, clone 154, from mouse,
Species Reactivity
human
Application
ELISA
western blot
Anti-human brain natriuretic peptide, clone 26, clone 26, from mouse,
Species Reactivity
human
Application
ELISA
western blot

Proteins

Product Number
Description
Species
Brain Natriuretic Peptide-32 human, ≥97% (HPLC), powder,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Nppb,
Species
mouse