MilliporeSigma

NQO1

NAD(P)H dehydrogenase, quinone 1

Synonyms:
DHQU, DIA4, DTD, NMOR1, NMORI, QR1
Species:
UniProtKB ID:
Gene ID:
  • Human(1728) Summary: This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
  • Mouse(18104) NAD(P)H dehydrogenase, quinone 1
  • Rat(24314) NAD(P)H dehydrogenase, quinone 1
  • chicken(769737) NAD(P)H dehydrogenase, quinone 1
  • domestic guinea pig(100135582) NAD(P)H dehydrogenase, quinone 1
  • domestic cat(101097859) NAD(P)H dehydrogenase, quinone 1
  • Zebrafish(322506) NAD(P)H dehydrogenase, quinone 1
  • cow(519632) NAD(P)H dehydrogenase, quinone 1
  • sheep(101121876) NAD(P)H dehydrogenase, quinone 1
  • naked mole-rat(101711262) NAD(P)H dehydrogenase, quinone 1
  • dog(610935) NAD(P)H dehydrogenase, quinone 1

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ELISA

Product Number
Description
Species
Human NQO-1 ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-NQO1 antibody produced in mouse, clone 1A11, ascites fluid,
Species Reactivity
human
Application
ELISA
flow cytometry

western blot
Monoclonal Anti-NQO1 antibody produced in mouse, clone 4D12, ascites fluid,
Species Reactivity
human
Application
ELISA
flow cytometry

immunohistochemistry

western blot
Anti-NQO1 Antibody, clone 1D12 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry

western blot
Anti-NQO1 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-NQO1 antibody produced in rabbit, ,
Species Reactivity
human, mouse
Application
immunofluorescence
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Menadione (K3), analytical standard,
Species
human
Menadione, meets USP testing specifications,
Species
human
Menadione, crystalline,
Species
human

Proteins

Product Number
Description
Species
DT Diaphorase (NQO1) human, lyophilized powder, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
Species
human
NQO1 human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Nqo1,
Species
mouse
MISSION® esiRNA, targeting human NQO1,
Species
human