PLA2G4A
phospholipase A2, group IVA (cytosolic, calcium-dependent)
Synonyms:
PLA2G4, cPLA2-alpha
Species:
Human PLA2G4A (5321), Mouse Pla2g4a (18783), Rat Pla2g4a (24653), dog PLA2G4A (480048), Horse PLA2G4A (100033889), cow PLA2G4A (525072), Zebrafish pla2g4a (559087), domestic guinea pig Pla2g4a (100715719), domestic cat PLA2G4A (101082033), chicken PLA2G4A (396394) ...More
UniProtKB ID:
Gene ID:
- Human(5321) Summary: This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles. [provided by RefSeq, Jul 2008]
- Mouse(18783) phospholipase A2, group IVA (cytosolic, calcium-dependent)
- Rat(24653) phospholipase A2, group IVA (cytosolic, calcium-dependent)
- dog(480048) phospholipase A2, group IVA (cytosolic, calcium-dependent)
- Horse(100033889) phospholipase A2, group IVA (cytosolic, calcium-dependent)
- cow(525072) phospholipase A2, group IVA (cytosolic, calcium-dependent)
- Zebrafish(559087) phospholipase A2, group IVA (cytosolic, calcium-dependent)
- domestic guinea pig(100715719) phospholipase A2, group IVA (cytosolic, calcium-dependent)
- domestic cat(101082033) phospholipase A2, group IVA (cytosolic, calcium-dependent)
- chicken(396394) phospholipase A2, group IVA (cytosolic, calcium-dependent)
- sheep(101111472) phospholipase A2, group IVA (cytosolic, calcium-dependent)
- naked mole-rat(101704061) phospholipase A2, group IVA (cytosolic, calcium-dependent)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-C-PLA2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-cPLA2 Antibody, clone 2F4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human
Application
affinity binding assay
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-PLA2G4A antibody produced in mouse, clone 10G5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-phospho-c-PLA2 (pSer505) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-PLA2G4A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry