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RPS6

ribosomal protein S6

Synonyms:
S6
Species:
UniProtKB ID:
Gene ID:
  • Human(6194) Summary: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
  • Mouse(20104) ribosomal protein S6
  • Rat(29304) ribosomal protein S6
  • dog(474722) ribosomal protein S6
  • Thale Cress(829298) 40S ribosomal protein S6-1
  • cow(787914) ribosomal protein S6
  • Thale Cress(834690) TIR-NBS-LRR class disease resistance protein
  • fruit fly(31700) Ribosomal protein S6
  • domestic cat(101098495) ribosomal protein S6
  • domestic guinea pig(100729373) ribosomal protein S6
  • Zebrafish(445028) ribosomal protein S6
  • naked mole-rat(101723295) ribosomal protein S6
  • chicken(396148) ribosomal protein S6

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-S6 Ribosomal Protein (RPS6) Antibody, clone 4C7P4, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunofluorescence
western blot
Anti-p-RPS6 (Ser240/244) Antibody, clone 2H10 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
bovine, canine, human, monkey, mouse, porcine
Application
affinity binding assay
flow cytometry

immunocytochemistry

immunohistochemistry

western blot
Anti-S6 Ribosomal Protein (phospho S240/244) antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP45, affinity isolated antibody,
Species Reactivity
bovine, chicken, dog, frog, human, mouse, pig, rabbit, rat
Application
immunohistochemistry
Anti-phospho-S6 Ribosomal Protein (pSer235) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Anti-phospho-S6 Ribosomal Protein (pSer240) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Rps6,
Species
mouse
MISSION® esiRNA, targeting human RPS6,
Species
human