MilliporeSigma
All Photos(3)

Documents

108413

Sigma-Aldrich

Methyl chloroacetate

99%

Sign Into View Organizational & Contract Pricing

Synonym(s):
Chloroacetic acid methyl ester, Methyl 2-chloroacetate
Linear Formula:
ClCH2COOCH3
CAS Number:
Molecular Weight:
108.52
Beilstein/REAXYS Number:
506255
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

vapor density

3.8 (vs air)

Quality Level

vapor pressure

10 mmHg ( 25 °C)
5.25 mmHg ( 20 °C)

assay

99%

autoignition temp.

869 °F

expl. lim.

18.5 %

refractive index

n20/D 1.422 (lit.)

bp

130 °C/740 mmHg (lit.)

mp

−33 °C (lit.)

solubility

H2O: insoluble
alcohol: miscible
diethyl ether: miscible

density

1.238 g/mL at 25 °C (lit.)

SMILES string

COC(=O)CCl

InChI

1S/C3H5ClO2/c1-6-3(5)2-4/h2H2,1H3

InChI key

QABLOFMHHSOFRJ-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
E16856M55909809934
Methyl chloroacetate 99%

108413

Methyl chloroacetate

Ethyl chloroacetate 99%

E16856

Ethyl chloroacetate

Methyl methacrylate contains ≤30 ppm MEHQ as inhibitor, 99%

M55909

Methyl methacrylate

Ethyl methyl carbonate battery grade, 99.9%, acid <10 ppm, H2O <10ppm

809934

Ethyl methyl carbonate

Quality Level

100

Quality Level

-

Quality Level

200

Quality Level

200

solubility

H2O: insoluble, diethyl ether: miscible, alcohol: miscible

solubility

-

solubility

-

solubility

-

refractive index

n20/D 1.422 (lit.)

refractive index

n20/D 1.421 (lit.)

refractive index

n20/D 1.414 (lit.)

refractive index

-

mp

−33 °C (lit.)

mp

−26 °C (lit.)

mp

−48 °C (lit.)

mp

-55 °C

bp

130 °C/740 mmHg (lit.)

bp

143 °C (lit.)

bp

100 °C (lit.)

bp

101 °C

General description

Methyl chloroacetate acts as extraction solvent during the separation of neutral compounds with concentration enhancement using coupling liquid–liquid semimicroextraction with micellar electrokinetic chromatography through on-capillary decomposition. It regenerates the PdCl2-CuCl2/activated carbon catalyst used for synthesis of dimethyl carbonate.

Application

Methyl chloroacetate was used in the preparation of (carboxymethyl) trimethylammonium chloride esters. It may be used in the synthesis of octakis-(carbethoxymethoxy)calix[8]arene.

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Dam. 1 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

3 - Flammable liquids

wgk_germany

WGK 3

flash_point_f

116.6 °F - closed cup

flash_point_c

47 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Customers Also Viewed

Slide 1 of 2

1 of 2

Benzyl chloroacetate 99%

Sigma-Aldrich

349712

Benzyl chloroacetate

Ethyl bromoacetate purum, ≥97.0% (GC)

Sigma-Aldrich

17020

Ethyl bromoacetate

A W Lloyd et al.
The Journal of pharmacy and pharmacology, 46(9), 704-707 (1994-09-01)
Glycinebetaine and N-modified betaines have been previously shown to be effective at reducing leakage from liposomes on freeze-thaw procedures. This study involved the preparation of a series of other modified betaines and the comparison of their abilities to reduce leakage
Nonionogenic star-shaped calix [8] arenes: Synthesis and ionophore properties.
Ten'kovtsev AV and Razina AB.
Russian Journal of Applied Chemistry, 82(9), 1615-1619 (2009)
The effects of promoters on catalytic properties and deactivation-regeneration of the catalyst in the synthesis of dimethyl carbonate.
Ruixia J, et al.
Applied Catalysis A: General, 238(1), 131-139 (2003)
Tianlin Wang et al.
Journal of chromatography. A, 1147(1), 105-110 (2007-03-03)
This paper reports the use of methyl chloroacetate (MCA) as an extraction solvent for coupling liquid-liquid semimicroextraction (LLsME) with micellar electrokinetic chromatography (MEKC) through on-capillary decomposition for the separation of neutral compounds with concentration enhancement. Alkylphenones of C(8), C(10) and
Daniele Tedesco et al.
Chirality, 27(12), 914-918 (2015-10-09)
Caffeic acid-derived polyethers are a class of natural products isolated from the root extracts of comfrey and bugloss, which are endowed with intriguing pharmacological properties as anticancer agents. The synthesis of new polyether derivatives is achieved through ring-opening polymerization of

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service