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109630

1-Hydroxy-2-naphthoic acid

≥97.0%

Synonym(s):

α-Hydroxynaphthoic acid

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About This Item

Linear Formula:
HOC10H6CO2H
CAS Number:
Molecular Weight:
188.18
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
201-674-0
Beilstein/REAXYS Number:
974438
MDL number:
Assay:
≥97.0%
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InChI key

SJJCQDRGABAVBB-UHFFFAOYSA-N

InChI

1S/C11H8O3/c12-10-8-4-2-1-3-7(8)5-6-9(10)11(13)14/h1-6,12H,(H,13,14)

SMILES string

OC(=O)c1ccc2ccccc2c1O

assay

≥97.0%

mp

195-200 °C (dec.) (lit.)

solubility

alcohol: freely soluble, benzene: freely soluble, cold water: insoluble, diethyl ether: freely soluble

functional group

carboxylic acid

Quality Level

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General description

1-Hydroxy-2-naphthoic acid is produced by the transformation of phenanthrene by NCIB 9816 clones.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

302.0 °F - closed cup

flash_point_c

150 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves


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K Hanna et al.
Chemosphere, 70(2), 178-186 (2007-08-11)
The adsorption of naphthoic acids to iron oxides and hydroxides influences strongly their mobility in soils and sediments. Sorption of 1-hydroxy-2-naphthoic acid (HNA) to three iron oxides was examined over a wide range of conditions (pH, ionic strength, sorbate and
Marta Ferraroni et al.
The FEBS journal, 280(7), 1643-1652 (2013-02-07)
The salicylate 1,2-dioxygenase (SDO) from the bacterium Pseudaminobacter salicylatoxidans BN12 is a versatile gentisate 1,2-dioxygenase (GDO) that converts both gentisate (2,5-dihydroxybenzoate) and various monohydroxylated substrates. Several variants of this enzyme were rationally designed based on the previously determined enzyme structure
Tony Hadibarata et al.
Journal of environmental management, 111, 115-119 (2012-07-28)
The biodegradation of benzo[a]pyrene (BaP) by using Polyporus sp. S133, a white-rot fungus isolated from oil-contaminated soil was investigated. Approximately 73% of the initial concentration of BaP was degraded within 30 d of incubation. The isolation and characterization of 3
Bibiana M Coppotelli et al.
Microbial ecology, 59(2), 266-276 (2009-07-18)
The present study describes the phenanthrene-degrading activity of Sphingomonas paucimobilis 20006FA and its ability to promote the bioavailability of phenanthrene. S. paucimobilis 20006FA was isolated from a phenanthrene-contaminated soil microcosm. The strain was able to grow in liquid mineral medium
Mario Cazzola et al.
Clinical pharmacokinetics, 41(1), 19-30 (2002-02-05)
Salmeterol is an inhaled long-acting selective beta(2)-adrenoceptor agonist that is commercially available as the xinafoate (1-hydroxy-2-naphthoic acid) salt of the racemic mixture of the two optical isomers, (R)- and (S)-, of salmeterol. It acts locally in the lung through action

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